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Specifications, Properties, Uses, SDS of Sodium Salicylate USP BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 54-21-7. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Sodium Salicylate for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Sodium Salicylate CAS Number 54-21-7
For Properties Specifications Uses of Sodium Salicylate Click Properties, Specifications, Uses, Price, Process of Sodium Salicylate Manufacturer.
For For SDS MSDS Sheet of Sodium Salicylate Click SDS Safety Data Sheet MSDS Sheet of Sodium Salicylate Manufacturer.
The Properties, Specifications, Monograph and Uses of Sodium Salicylate:
CAS Number: 54-21-7, EINECS EC Number: 200-198-0, Molecular Formula: HOC6H4COONa, Molecular Weight: 160.11, HS Code 29182120 or 29189900
Sodium Salicylate USP Grade Specifications:
C7H5NaO3 --- 160.10
Benzoic acid, 2-hydroxy-, monosodium salt;
Monosodium salicylate CAS 54-21-7
DEFINITION
Sodium Salicylate contains NLT 98.0% and NMT 102.0% of sodium salicylate (C7H5NaO3), calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption
B. Identification Tests-General, Sodium
C. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
ASSAY
To pass the test by Chromatography.
Acceptance criteria: 98.0% to 102.0% on the anhydrous basis
Sample solution: 1.0 g of Sodium Salicylate in 20 mL of water
Analysis: Add 1 mL of hydrochloric acid to the Sample solution and filter the liquid.
Acceptance criteria: NMT 0.15 mL of 0.10 N iodine is required to produce a yellow color in the filtrate.
Organic Impurities: To pass the test by Chromatography.
Water Determination: NMT 0.5%
Packaging and Storage: Preserve in well-closed, light-resistant containers.
Specifications of Sodium Salicylate BP Ph Eur Grade
C7H5NaO3 -- 160.1 -- 54-21-7
Action and use: Anti-inflammatory; analgesic.
DEFINITION
Sodium 2-hydroxybenzenecarboxylate.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or small, colourless crystals or shiny flakes.
Solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent).
IDENTIFICATION
First identification A, C.
Second identification B, C.
A. Infrared absorption spectrophotometry.
B. Solution S (see Tests) gives the reactions of salicylates.
C. It gives reaction (b) of sodium.
TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water prepared from distilled water and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution BY6.
Acidity: To 20 ml of solution S add 0.1 ml of phenol red solution. The solution is yellow. Not more than 2.0 ml of 0.01 M sodium hydroxide is required to change the colour of the indicator to violet-red.
Chlorides: Maximum 200 ppm.
Sulphates: Maximum 600 ppm.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.00 g by drying in an oven at 105C.
The MSDS-SDS Hazard Statement of Sodium Salicylate:
Sodium Salicylate SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 08-Aug-21
1. Product Identification
Product Name & Other Names: Sodium Salicylate or 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt.
CAS No.: 54-21-7
EINECS EC Number: 200-198-0
Molecular Weight: 160.1
Chemical Formula: HOC6H4COONa
Relevant uses and uses advised against (if any): Industrial use only.
Suppliers: As per letterhead
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
Precautionary statements:
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
P501: Dispose of contents/container to authorized agents only.
3. Composition/Information on Ingredients
Product Name & Other Names: Sodium Salicylate or 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt.
CAS No.: 54-21-7
EINECS EC Number: 200-198-0
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not applicable.
Products of Combustion: Fumes, Metallic Oxide Carbon dioxide & Carbon Monoxide.
Fire: Sodium Salicylate is slightly flammable on heating.
Explosion: Slightly explosive on heating.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Use means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. On decomposition it may emit carbon monoxide. Containers may explode on heating.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, acids, strong bases, ferric salts, lead acetate, lead, lime water, silver nitrate, iodine. Keep away from heat and sun light.
8. Exposure Controls/Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Colorless white powder flakes or crystals.
Odor: It is odorless.
Odor threshold: Not available.
pH: 5-6
Relative density: about 2.5
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is soluble in water.
Viscosity: Not available.
Molecular Weight: 160.1
Molecular formula: HOC6H4COONa
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits carbon monoxide & fumes when heated to decomposition. It may form metallic oxide harmful gases.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, acids, strong bases, ferric salts, lead acetate, lead, lime water, silver nitrate, iodine.
Conditions to Avoid: Incompatible materials, light, dust generation, excess heat, exposure to moist air or water.
11. Toxicological Information
Toxicity data
ORL-RAT LD50 930 mg kg-1
ORL-Mouse LD50 540 mg kg-1
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Mutagenic effects have occurred in experimental animals.
Teratogenic Effects: Teratogenic effects have occurred in experimental animals.
Developmental Toxicity: Adverse reproductive effects have occurred in experimental animals.
12. Ecological Information
Toxicity to fish: LC50 - Pimephales promelas (fathead minnow) - 1.370 mg/l - 96 h
Environmental Fate: This substance is expected to have a high biological oxygen demand. It is readily biodegradable and has low bioconcentration potential.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with legal requirements.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
Sea Transport IMDG/IMO: Not regulated.
Air transport ICAO/IATA: Not regulated.
15. Regulatory Information
SARA Codes: CAS # 54-21-7: immediate, delayed. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Sodium Salicylate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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