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Specifications, Properties, Uses, SDS of Trisodium Phosphate or Sodium Phosphate Tribasic USP NF Analytical Reagent FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 10101-89-0 for Dodecahydrate and 7601-54-9 for Anhydrous. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Trisodium Phosphate or Sodium Phosphate Tribasic for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Trisodium Phosphate or Sodium Phosphate Tribasic CAS Number 10101-89-0 for Dodecahydrate and 7601-54-9 for Anhydrous
For Properties Specifications Uses of Trisodium Phosphate or Sodium Phosphate Tribasic Click Properties, Specifications, Uses, Price, Process of Trisodium Phosphate or Sodium Phosphate Tribasic Manufacturer.
For For SDS MSDS Sheet of Trisodium Phosphate or Sodium Phosphate Tribasic Click SDS Safety Data Sheet MSDS Sheet of Trisodium Phosphate or Sodium Phosphate Tribasic Manufacturer.
We supply as under:
Sodium Phosphate Monobasic or Monosodium Phosphate
Sodium Phosphate Dibasic or Disodium Phosphate
Sodium Phosphate Tribasic or Trisodium Phosphate (You are here).
The Properties, Specifications, Monograph and Uses of Trisodium Phosphate or Sodium Phosphate Tribasic:
CAS Number 10101-89-0 for Dodecahydrate and 7601-54-9 for Anhydrous, EINECS EC Number 231-509-8, HS Code 28352990 or 28352930 or 283533**, Molecular Weight 380.12, Chemical Formula Na3PO4-12H2O
Trisodium phosphate (TSP) is the inorganic compound with the chemical formula Na3PO4. It is a white, granular or crystalline solid, highly soluble in water, producing an alkaline solution. TSP is used as a cleaning agent, builder, lubricant, food additive, stain remover, and degreaser. Sodium phosphates including monosodium phosphate, disodium phosphate, and trisodium phosphate are approved as food additives in the EU. They are commonly used as acidity regulators and have the collective E number E339The United States Food and Drug Administration lists sodium phosphates as generally recognized as safe.
Tribasic Sodium Phosphate USP NF Grade Specification:
Na3PO4 (anhydrous) --- 163.94
Trisodium phosphate, monohydrate --- 181.96
Phosphoric acid, trisodium salt, dodecahydrate;
Trisodium phosphate, dodecahydrate --- 380.13 CAS 10101-89-0
Anhydrous CAS 7601-54-9
DEFINITION
Tribasic Sodium Phosphate is anhydrous or contains one to twelve molecules of water of hydration. Na3PO4 (anhydrous) and Na3PO4-H2O (monohydrate) contain NLT 97.0% of Na3PO4 calculated on the ignited basis. Na3PO4-12H2O (dodecahydrate) contains NLT 92.0% of Na3PO4, calculated on the ignited basis.
IDENTIFICATION
A. Identification Tests-General, Sodium and Phosphate:
ASSAY
Procedure
Sample: 5.5 g of Tribasic Sodium Phosphate, on the anhydrous basis
Blank: 100.0 mL of 1 N hydrochloric acid, accurately measured
Titrimetric system
Mode: Residual titration
Titrant: 1 N sodium hydroxide
Endpoint detection: Potentiometric
Analysis: Transfer the Blank to a 400-mL beaker and titrate with the Titrant to the endpoint at a pH of 7.0. Record as the volume consumed and designate as A. Transfer the Sample to a 400-mL beaker, add 100.0 mL of 1 N hydrochloric acid, and stir until dissolved. Pass a stream of carbon dioxide-free air, in fine bubbles, through the solution for 30 min to expel carbon dioxide, covering the beaker loosely to prevent any loss by spraying. Wash the cover and sides of the beaker with a few mL of water.
Titrate the excess acid potentiometrically with the Titrant to the inflection point at a pH of 4. Record the burette reading and designate as B. Protect the solution from carbon dioxide absorbed from the air and continue the titration with 1 N sodium hydroxide VS to the inflection point at a pH of 8.8. Record the burette reading, and designate as C.
Calculate the amount of Titrant consumed by the Sample to the first inflection point, correcting for the Blank (V1 = A - B) and the amount of Titrant consumed by the Sample between the two inflection points (V 2 = C - B). If ;V 1 is equal to or greater than 2V 2, calculate the amount of Na3PO4 in the portion of Sample taken:
D = V 2 x N x F
V 2 = volume of Titrant consumed between the two inflection points (mL)
N = actual normality of the Titrant (mEq/mL)
F = equivalency factor, 163.9 mg/mEq
If V 1 is less than 2V 2, calculate the amount of Na3PO4 in the portion of Sample taken:
D = (V 1 - V 2) x N x F
V 1 = volume of the Titrant consumed to the first inflection point, correcting for the Blank (mL)
N = actual normality of the Titrant (mEq/mL)
F = equivalency factor, 163.9 mg/mEq
Calculate the percentage of Na3PO4 on the ignited basis in the portion of Tribasic Sodium Phosphate taken:
Result = [10/(100 - L)] x (D/W)
L = percentage calculated in the test for Loss on Ignition.
D = amount of Na3PO4 found (mg)
W = weight of the Sample (g)
Acceptance criteria: NLT 97.0% of Na3PO4 on the ignited basis. Na3PO4-12H2O (dodecahydrate) contains NLT 92.0% of Na3PO4 on the ignited basis.
Sample: 2 g
Analysis: Dry the Sample at 110C for 5 h, and then ignite at 800C for 30 min.
Acceptance criteria: The anhydrous form loses NMT 2.0% of its weight, the monohydrate loses 8.0% to 11.0% of its weight, and the dodecahydrate loses 45.0% to 57.0% of its weight.
Arsenic: To pass the test.
Acceptance criteria: NMT 3 ppm
Insoluble Substances:
Sample solution: Dissolve a portion equivalent to 10.0 g of anhydrous tribasic sodium phosphate in 100 mL of hot water.
Analysis: Filter the Sample solution through a tared filtering crucible. [Note: Do not use glass.] Wash the insoluble residue with hot water, and dry at 105C for 2 h.
Acceptance criteria: The weight of the residue so obtained does not exceed 20 mg (0.2%).
Packaging and Storage: Preserve in tight containers. No storage requirements specified.
Sodium Phosphate Tribasic FCC Food Grade
Trisodium Phosphate
Na3PO4 Formula wt, anhydrous 163.94
Na3PO4-12H2O Formula wt, dodecahydrate 380.12
INS: 339(iii) CAS: anhydrous [7601-54-9]
CAS: dodecahydrate [10101-89-0]
DESCRIPTION
Sodium Phosphate, Tribasic, occurs as white crystals or granules or as a crystalline material. It may be anhydrous or contain 1 to 12 molecules of water of hydration. The formula for a crystalline material is approximately 4(Na3PO4-12H2O)- NaOH. It is freely soluble in water, but is insoluble in alcohol. The pH of a 1:100 aqueous solution is between 11.5 and 12.5.
Function: Antimicrobial; buffer; emulsifier; nutrient.
REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Sodium and for Phosphate.
Assay: Anhydrous and Monohydrate: Not less than 97.0% of Na3PO4, calculated on the ignited basis; Dodecahydrate: Not less than 90.0% of Na3PO4, calculated on the ignited basis.
Arsenic: Not more than 3 mg/kg.
Fluoride: Not more than 0.005%.
Insoluble Substances: Not more than 0.2%.
Lead: Not more than 4 mg/kg.
Loss on Ignition Anhydrous: Not more than 2.0%; Monohydrate: Between 8.0% and 11.0%; Dodecahydrate: Between 45.0% and 57.0%.
Specifications of Sodium Phosphate Tribasic Dodecahydrate Analytical Reagent
Na3PO4-12H2O
Formula Wt 380.12
CAS Number 10101-89-0
NOTE. This salt, when stored under ordinary conditions, may lose some water of crystallization. Any loss in water will result in an assay of more than 100% Na3PO4-12H2O but does not affect the determination of the relative amount of free alkali present.
REQUIREMENTS
Assay: 98.0-102.0% Na3PO4-12H2O
MAXIMUM ALLOWABLE
Excess alkali (as NaOH): 2.5%
Insoluble matter: 0.01%
Chloride (Cl): 0.001%
Nitrogen compounds (as N): 0.001%
Sulfate (SO4): 0.01%
Heavy metals (as Pb): 0.001%
Iron (Fe): 0.001%
The MSDS-SDS Hazard Statement of Trisodium Phosphate or Sodium Phosphate Tribasic:
Trisodium Phosphate SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet Sodium Phosphate Tribasic 07-Aug-21
1. Product Identification
Product Name & Other Names: Trisodium phosphate 12-Hydrate or Sodium phosphate tribasic or Phosphoric acid trisodium salt or Dodecahydrate trisodium Phosphate.
CAS No.: 7601-54-9 (Anhydrous) 10101-89-0 (Dodecahydrate)
EINECS EC Number: 231-509-8
Molecular Weight: 163.94 for Anhydrous and 380.12 for Dodecahydrate
Chemical Formula: Na3PO4 for Anhydrous and Na3PO4-12H2O for Dodecahydrate
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity - single exposure, Target Organs - Respiratory system. Category 3, H335
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Words: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P264: Wash … thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P362: Take off contaminated clothing and wash before reuse.
3. Composition/Information on Ingredients
Product Name & Other Names: Trisodium phosphate 12-Hydrate or Sodium phosphate tribasic or Phosphoric acid trisodium salt or Dodecahydrate trisodium Phosphate.
CAS No.: 7601-54-9
EINECS EC Number: 231-509-8
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do NOT induce vomiting. Give large amounts of water. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: Not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Use means suitable for extinguishing surrounding.
Extinguishing Media Not recommended: None specified.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Trisodium phosphate or Tri Sodium Phosphate:
AIHA Workplace Environmental Exposure Limit: 5 mg/m3 (15-minute STEL)
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a full-face piece respirator with high efficiency particulate filter (NIOSH type N100 filter). If oil particles (e.g., lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White crystalline solid.
Odor: Odorless.
Odor threshold: Not available.
pH: Strongly alkaline.
Relative density: around 1.62
Boiling Point: Decomposes.
Melting Point: 73.3 - 76.7C (163 - 171F)
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Appreciable (> 10%)
Viscosity: Not available.
Molecular Weight: 163.94 for Anhydrous and 380.12 for Dodecahydrate
Chemical Formula: Na3PO4 for Anhydrous and Na3PO4-12H2O for Dodecahydrate.
10. Stability and Reactivity
Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Sodium and phosphorus oxides may form when heated to decomposition.
Hazardous Polymerization: Will not occur for Tri Sodium Phosphate.
Incompatibilities: Trisodium Phosphate reacts violently with water and acids to liberate heat.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicity to Animals: Trisodium Phosphate, Dodecahydrate: 7400 mg/kg oral rat LD50.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC NTP ACGIH OSHA.
Teratogenic Effects: Not available.
Mutagenic Effects: Investigated as a mutagen.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to fish: No information available.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with law.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
Air Transport IATA/ICAO: Not regulated.
Sea Transport IMDG/IMO: Not regulated.
15. Regulatory Information
USA:
California Proposition 65: Not listed.
SARA 311/312: Acute health hazard. See section 2.
16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Trisodium Phosphate or Sodium Phosphate Tribasic Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals. Check.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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