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Specifications, Properties, Uses, SDS of Sodium Chloride USP BP Ph Eur IP Analytical Reagent FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 7647-14-5. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Sodium Chloride for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Sodium Chloride CAS Number 7647-14-5
For Properties Specifications Uses of Sodium Chloride Click Properties, Specifications, Uses, Price, Process of Sodium Chloride Manufacturer.
For For SDS MSDS Sheet of Sodium Chloride Click SDS Safety Data Sheet MSDS Sheet of Sodium Chloride Manufacturer.
The Properties, Specifications, Monograph and Uses of Sodium Chloride:
CAS Number 7647-14-5, Molecular Weight 58.44, Chemical Formula NaCl, HS Code 28273990 or 25010090
Sodium chloride commonly known as salt is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. In its edible form of table salt, it is commonly used as a condiment and food preservative. Large quantities of sodium chloride are used in many industrial processes, and it is a major source of sodium and chlorine compounds used as feedstocks for further chemical syntheses. It is also used in medicine and pharmaceutical industries.
Sodium Chloride USP Grade Specifications:
NaCl --- 58.44
Sodium Chloride CAS 7647-14-5
DEFINITION
Sodium Chloride contains NLT 99.0% and NMT 100.5% of sodium chloride (NaCl), calculated on the dried basis.
IDENTIFICATION
A. Identification Tests General Sodium: Meets the requirements
B. Chloride:
Sample solution: 3 mg of Sodium Chloride in 2 mL of water
Analysis: Acidify the Sample solution with diluted nitric acid and add 0.4 mL of silver nitrate. Shake, and allow to stand. A curdled, white precipitate is formed. Centrifuge, wash the precipitate with three 1-mL portions of water, and discard the washings. Carry out this operation rapidly in subdued light, disregarding the fact that the supernatant may not become perfectly clear. Suspend the precipitate in 2 mL of water and add 1.5 mL of 10 N ammonium hydroxide.
Acceptance criteria: The precipitate dissolves easily with the possible exception of a few large particles, which dissolve more slowly.
ASSAY
Procedure
Sample: 50 mg of Sodium Chloride
Analysis: Dissolve the Sample in 50 mL of water, and titrate with 0.1 N silver nitrate, determining the endpoint potentiometrically. Each mL of 0.1 N silver nitrate is equivalent to 5.844 mg of sodium chloride (NaCl).
Acceptance criteria: 99.0% to 100.5% on the dried basis
Acceptance criteria: The fluorescence of the Sample solution does not exceed that of the Standard solution (0.2 ppm).
Arsenic: NMT 1 ppm
Barium: To pass the test.
Ferrocyanides: To pass the test.
Iodides: To pass the test.
Iron: To pass the test. --- (NMT 2 ppm).
Limit of Bromides: To pass the test. --- (NMT 100 ppm).
Limit of Phosphates: To pass the test. --- (NMT 25 ppm).
Limit of Potassium (where it is labeled as intended for use in the manufacture of injectable dosage forms, peritoneal dialysis solutions, hemodialysis solutions, or hemofiltration solutions): To pass the test.
Acceptance criteria: NMT 500 ppm
Magnesium and Alkaline-Earth Metals: To pass the test. --- (NMT 100 ppm, calculated as Ca).
Nitrites: To pass the test.
Sulfate: To pass the test.
Appearance of Solution: Dissolve 20.0 g of Sodium Chloride in carbon dioxide-free water, and dilute with the same solvent to 100.0 mL. This solution is clear and colorless.
Acidity or Alkalinity: To pass the test.
Loss on Drying:
Sample: 1.000 g
Analysis: Dry the Sample in an oven at 105C for 2 h.
Acceptance criteria: NMT 0.5%
Bacterial Endotoxins Test: To pass the test.
Sterility Tests: Where the label states that Sodium Chloride is sterile, it meets the requirements for Sterility under the relevant dosage form monograph(s) in which Sodium Chloride is used.
Packaging and Storage: Preserve in well-closed containers.
Specifications of Sodium Chloride BP Grade
NaCl -- 58.44 -- CAS 7647-14-5
Action and use: Used in treatment of electrolyte deficiency.
DEFINITION
Content: 99.0 per cent to 100.5 per cent (dried substance).
CHARACTERS
Appearance
White or almost white, crystalline powder or colourless crystals or white or almost white pearls.
Solubility
Freely soluble in water, practically insoluble in anhydrous ethanol.
IDENTIFICATION
A. It gives the reactions of chlorides.
B. It gives the reactions of sodium.
TESTS
Solution S: If the substance is in the form of pearls crush before use.
Dissolve 20.0 g in carbon dioxide-free water prepared from distilled water and dilute to 100.0 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 20 ml of solution S add 0.1 ml of bromothymol blue solution. Not more than 0.5 ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Bromides: Maximum 100 ppm.
Ferrocyanides: Dissolve 2.0 g in 6 ml of water. Add 0.5 ml of a mixture of 5 ml of a 10 g/l solution of ferric ammonium sulphate in a 2.5 g/l solution of sulphuric acid and 95 ml of a 10 g/l solution of ferrous sulphate. No blue colour develops within 10 min.
Iodides: Moisten 5 g by the drop wise addition of a freshly prepared mixture of 0.15 ml of sodium nitrite solution, 2 ml of 0.5 M sulphuric acid , 25 ml of iodide-free starch solution and 25 ml of water. After 5 min, examine in daylight. The mixture shows no blue colour.
Nitrites: To 10 ml of solution S add 10 ml of water. The absorbance is not greater than 0.01 at 354 nm.
Phosphates: Maximum 25 ppm.
Sulphate: Maximum 200 ppm.
Aluminium: Maximum 0.2 ppm, if intended for use in the manufacture of peritoneal dialysis solutions, hem dialysis solutions or haemofiltration solutions.
Arsenic: Maximum 1 ppm, determined on 5 ml of solution S.
Barium: To 5 ml of solution S add 5 ml of distilled water and 2 ml of dilute sulphuric acid. After 2 h, any opalescence in the solution is not more intense than that in a mixture of 5 ml of solution S and 7 ml of distilled water.
Iron: Maximum 2 ppm, determined on solution S.
Magnesium and alkaline-earth metals: Maximum 100 ppm, calculated as Ca and determined on 10.0 g.
Potassium: maximum 5.00 x 102 ppm, if intended for use in the manufacture of parenteral dosage forms or hem-dialysis, haemofiltration or peritoneal dialysis solutions.
Atomic emission spectrometry: To pass the test
Heavy metals: Maximum 5 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C for 2h.
Bacterial endotoxins: Less than 5 IU/g, if intended for use in the manufacture of parenteral dosage forms without a further appropriate procedure for removal of bacterial endotoxins.
Specifications of NaCl, Sodium Chloride IP Grade:
Dry Basis Assay: 99.0% - 100.5%
Description: White, crystalline powder.
Solubility: Freely soluble in water; practically insoluble in ethanol.
Acidity or alkalinity: Passes Test
Clarity and Colour of Solution: Clear & colourless solution (10% w/w).
Arsenic: 1 ppm maximum.
Barium: Passes Test
Bromide: 0.1% maximum.
Calcium & Magnesium as Ca: 50 ppm maximum.
Ferro cyanide: Passes Test
Heavy Metals: 5 ppm maximum.
Iodide: Passes Test
Iron: 20 ppm maximum.
Loss on Drying: 1% maximum.
Potassium: 0.1% maximum.
Sodium Chloride Analytical Regent Specifications
Analytical Reagent AR Chemicals
ACS Specifications
Sodium Chloride
NaCl
Formula Wt 58.44
CAS Number 7647-14-5
REQUIREMENTS
Assay: min 99.0% NaCl
pH of a 5% solution: 5.0-9.0 at 25C
MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Iodide (I): 0.002%
Bromide (Br): 0.01%
Chlorate and nitrate (as NO3): 0.003%
Nitrogen compounds (as N): 0.001%
Phosphate (PO4): 5 ppm
Sulfate (SO4): 0.004%
Barium (Ba): Passes test
Heavy metals (as Pb): 5 ppm
Iron (Fe): 2 ppm
Calcium (Ca): 0.002%
Magnesium (Mg): 0.001%
Potassium (K): 0.005%
The MSDS-SDS Hazard Statement of Sodium Chloride:
Sodium Chloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 06-Aug-21
Section 1 - Chemical Product and Identification
Product Name & Other Names: Sodium Chloride or Common salt or Halite or Rock salt or Saline or Salt or Sea salt or Table salt.
CAS Number: 7647-14-5
EINECS EC Code: 231-598-3
Chemical Formula: NaCl
Molecular Weight: 58.44
Relevant uses and uses advised against (if any): Laboratory Chemicals and Industrial Manufacturing Use.
Supplier: As per letterhead.
Section 2 - Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Section 3 - Composition, Information on Ingredients
Product Name & Other Names: Sodium Chloride or Common salt or Halite or Rock salt or Saline or Salt or Sea salt or Table salt.
CAS#: 7647-14-5
EINECS EC No.: 231-598-3
Section 4 - First Aid Measures
Always seek medical advice after the first aid treatment.
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid. Wash mouth out with water.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: None.
Section 5 - Fire Fighting Measures
General Information: Water runoff can cause environmental damage. Dike and collect water used to fight fire. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Substance is noncombustible.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide or chemical foam.
Extinguishing Media Not recommended: None specified.
Special hazards arising from the substance: Hydrogen chloride gas, Sodium oxides.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6 - Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7 - Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, iron, or steel, building materials (such as cement), bromine, or trifluoride. Store protected from moisture.
Section 8 - Exposure Controls, Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Engineering Controls: Good general ventilation should be sufficient to control airborne levels. Facilities storing or utilizing the material should be equipped with an eyewash facility and a safety shower.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9 - Physical and Chemical Properties
Appearance: Solid. Colorless or white crystalline powder.
Odor: Odorless
Odor threshold: Not available.
pH: Not available.
Relative density: around 2.16
Boiling Point: 2575 deg F
Freezing/Melting Point:1474 deg F
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Formula: NaCl
Molecular Weight: 58.44
Section 10 - Stability and Reactivity
Chemical Stability: Stable.
Conditions to Avoid: High temperatures, exposure to moist air or water.
Incompatibilities with Other Materials: It reacts with most non-noble metals such as iron or steel, building materials (such as cement), bromine, or trifluoride. Potentially explosive reaction with dichloro-maleic anhydride + urea. Electrolysis of mixtures with nitrogen compounds may form explosive nitrogen tri-chloride.
Hazardous Decomposition Products: Toxic fumes of chlorine or hydrogen chloride and sodium oxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
LD50 Oral - Rat - 3,550 mg/kg (Sodium chloride)
LC50 Inhalation - Rat - 1 h - > 42,000 mg/m3 (Sodium chloride)
LD50 Dermal - Rabbit - > 10,000 mg/kg( Sodium chloride)
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12 - Ecological Information
Toxicity to fish: LC50 - Lepomis macrochirus (Bluegill) - 5,840 mg/l - 96 h
Toxicity to daphnia and other aquatic invertebrates:
NOEC - Daphnia (water flea) - 1,500 mg/l - 7 d(Sodium chloride)
LC50 - Daphnia magna (Water flea) - 1,661 mg/l - 48 h(Sodium chloride)
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
Section 14 - Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMDG/IMO: Not dangerous goods.
Air Transport IATA/ICAO: Not dangerous goods.
Section 15 - Regulatory Information
USA Regulations:
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Sodium Chloride Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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