Specifications, Uses, SDS of Povidone Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Povidone or Polyvinylpyrrolidone USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 9003-39-8.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Povidone for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

The Properties, Specifications, Monograph and Uses of Povidone or Polyvinylpyrrolidone:

PVP K-30 and PVP K90 Povidone or Polyvinylpyrrolidone: CAS Number: 9003-39-8, Molecular Formula: (C6H9NO)n, Molecular Weight: polymer, HS Code ---**

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer. Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It also acts as a disintegrant and tablet binder. It appears as white to off-white hygroscopic powder in its pure form and is readily soluble in water. PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers.

Povidone USP Grade Specifications:
(C6H9NO)n
2-Pyrrolidinone, 1-ethenyl-, homopolymer;
1-Vinyl-2-pyrrolidinone polymer;
Poly [(2-oxo-1-pyrrolidinyl)ethylene] CAS 9003-39-8

DEFINITION
Povidone is a chain polymer of 1-vinyl-2-pyrrolidone. It contains NLT 11.5% and NMT 12.8% of nitrogen (N: 14.01), calculated on the anhydrous basis. It has the nominal K-value of NLT 10 and NMT 120. The nominal K-value is shown on the label.

IDENTIFICATION
A. Infrared Absorption
B.
Sample solution: 20 mg/mL of Povidone
Analysis: To 10 mL of the Sample solution, add 20 mL of 1 N hydrochloric acid and 5 mL of potassium dichromate.
Acceptance criteria: An orange-yellow precipitate is formed.
C.
Solution A: Dissolve 75 mg of cobalt nitrate and 300 mg of ammonium thiocyanate in 2 mL of water.
Sample solution: 20 mg/mL of Povidone
Analysis: Combine Solution A and 5 mL of the Sample solution, and render the resulting solution acidic by the addition of 3 N hydrochloric acid.
Acceptance criteria: A pale blue precipitate is formed.
D.
Sample solution: 5 mg/mL of Povidone
Analysis: To 5 mL of the Sample solution, add a few drops of iodine.
Acceptance criteria: A deep red color is produced.
E.
Sample solution: 50 mg/mL of Povidone in water
Acceptance criteria: The substance dissolves.

Specifications of Povidone BP Ph Eur Grade
C6nH9n+2NnOn --- CAS 9003-39-8
Action and use: Disinfectant.

DEFINITION
a-Hydro-w-hydropoly[1-(2-oxopyrrolidin-1-yl)ethylene]. It consists of linear polymers of 1-ethenylpyrrolidin-2-one.
Content: 11.5 per cent to 12.8 per cent of nitrogen (N; Ar 14.01) (anhydrous substance). The different types of povidone are characterised by their viscosity in solution expressed as a K-value.

CHARACTERS
Appearance: White or yellowish-white, hygroscopic powder or flakes.
Solubility: Freely soluble in water, in ethanol (96 per cent) and in methanol, very slightly soluble in acetone.

IDENTIFICATION
First identification A, E.
Second identification B, C, D, E.
A. Infrared absorption spectrophotometry
B. To 0.4 ml of solution S1 (see Tests) add 10 ml of water, 5 ml of dilute hydrochloric acid and 2 ml of potassium dichromate solution. An orange-yellow precipitate is formed.
C. To 1 ml of solution S1 add 0.2 ml of dimethylaminobenzaldehyde solution and 0.1 ml of sulphuric acid. A pink colour is produced.
D. To 0.1 ml of solution S1 add 5 ml of water and 0.2 ml of 0.05 M iodine. A red colour is produced.
E. To 0.5 g add 10 ml of water and shake. The substance dissolves.

TESTS
Solution S: Dissolve 1.0 g in carbon dioxide-free water and dilute to 20 ml with the same solvent. Add the substance to be examined to the water in small portions, stirring using a magnetic stirrer.
Solution S1: Dissolve 2.5 g in carbon dioxide-free water and dilute to 25 ml with the same solvent. Add the substance to be examined to the water in small portions, stirring using a magnetic stirrer.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 3.0 to 5.0 for solution S, for povidone having a stated K-value of not more than 30; 4.0 to 7.0 for solution S, for povidone having a stated K-value of more than 30.
Viscosity, expressed as K-value: To pass the test.
The K-value of povidone having a stated K-value of 15 or less is 85.0 per cent to 115.0 per cent of the stated value. The K-value of povidone having a stated K-value or a stated K-value range with an average of more than 15 is 90.0 per cent to 108.0 per cent of the stated value or of the average of the stated range.
Aldehydes: Maximum 5.0x100 ppm, expressed as acetaldehyde.
Peroxides: Maximum 400 ppm, expressed as H2O2.
Formic acid: To pass the liquid chromatography test.
Hydrazine: To pass the test.
Impurity A. R = CH=CH2: 1-ethenylpyrrolidin-2-one (1-vinylpyrrolidin-2-one): To pass the test.
Impurity B. R = H: pyrrolidin-2-one (2-pyrrolidone): To pass the test.
Heavy metals: Maximum 10 ppm.
Water: Maximum 5.0 per cent, determined on 0.500 g.
Sulphated ash: Maximum 0.1 per cent, determined on 1.0 g.

Polyvinylpyrrolidone FCC food Grade
PVP; Povidone; Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]
(C6H9NO)x
Lower mol wt range product ~40,000
Higher mol wt range product ~360,000
INS: 1201 CAS: 9003-39-8

DESCRIPTION
Polyvinylpyrrolidone occurs as a white to tan powder. It is a polymer of purified 1-vinyl-2-pyrrolidone produced catalytically. It is soluble in water, in alcohol, and in chloroform, and is insoluble in ether. The pH of a 1:20 aqueous solution is between 3 and 7.
Function: Clarifying agent; separation/filtration aid; stabilizer; bodying agent; tableting aid; dispersant; coating on fresh fruit.

REQUIREMENTS
Labeling: Indicate the K-value or the K-value range.
Identification:
A. Add 20 mL of 1 N hydrochloric acid and 5 mL of potassium dichromate TS to 10 mL of a 1:50 aqueous solution. An orange-yellow precipitate forms.
B. Add 5 mL of a 1:50 aqueous solution to 75 mg of cobalt nitrate and 300 mg of ammonium thiocyanate dissolved in 2 mL of water, mix, and then make the resulting solution acid with 2.7 N hydrochloric acid. A pale blue precipitate forms.
C. Add a few drops of iodine TS to 5 mL of a 1:200 aqueous solution. A deep red color appears.

Assay: Not less than 11.5% and not more than 12.8% as nitrogen (N), calculated on the anhydrous basis.
Aldehydes: (as acetaldehyde) Not more than 0.05%.
Hydrazine: Not more than 1 mg/kg.
K-Value: Between 27 and 32 for the lower-molecularweight-range product, and between 81 and 97 for the highermolecular-weight-range product.
Lead: Not more than 2 mg/kg.
Residue on Ignition: Not more than 0.1%.
Unsaturation: (as vinylpyrrolidone) Not more than 0.1%.
Water: Not more than 5.0%.

Polyvinylpyrrolidone or Povidone or PVPK30 or PVPK 90 SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 05-Aug-21

Product Name & Other Names: Polyvinylpyrrolidone or PVP or Povidone.
CAS Number: 9003-39-8
EINECS EC Number: -
Molecular Weight: -
Molecular Formula: (C6H9NO)n
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Polyvinylpyrrolidone or PVP or Povidone.
CAS Number: 9003-39-8

Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

Extinguisher Media: Use media suitable to extinguish surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Flammable Limits in Air % by Volume: N/A
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx)
Special Fire-fighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store cold to warm conditions, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing and reducing agents, Strong acids and bases.

Airborne Exposure Limits: None established. Ensure adequate ventilation. Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants low.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance and Odor: Solid beige powder.
Odor: Odor not defined.
Odor threshold: Not available.
pH: 5-8 at 10% water solution.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Not available.
Viscosity: Not available.
Molecular Weight: -
Molecular Formula: (C6H9NO)n

Stability: It is stable
Conditions to Avoid: Heat, humidity, Dust generation.
Incompatibility (Materials to Avoid): Strong oxidizing and reducing agents, Strong acids and bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization: Will not occur.

Acute toxicity:
LD50 Oral - rat - > 100,000 mg/kg
Carcinogenicity: This product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: LC50 >1000mg/liter over 48 hours exposure on kill fish.
Bioaccumulative potential: Does not bioaccumulate.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
Sea Transport IMDG/IMO: Not regulated.
Air Transport IATA: Not regulated.

USA:
California Proposition 65:
Chemicals known to cause cancer: Substance is not listed.
Chemicals known to cause reproductive toxicity for females: Substance is not listed.
Chemicals known to cause reproductive toxicity for males: Substance is not listed.
Chemicals known to cause developmental toxicity: Substance is not listed.
SARA 311/312 Hazards: See section 2.

Povidone or Polyvinylpyrrolidone Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Povidone or Polyvinylpyrrolidone USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 9003-39-8.

Povidone or Polyvinylpyrrolidone Manufacturers, Suppliers, Exporters, Wholesalers: