Specifications, Uses, SDS of Choline Chloride Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Choline Chloride USP Dietary Supplement and FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 67-48-1.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Choline Chloride for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

CAS Number: 67-48-1, EINECS EC Number: 200-655-4, Molecular Formula: C5H14ClNO, Molecular Weight: 139.62, HS Code 23099010 or 29231000

Choline chloride is an organic compound with the formula (CH3)3NCH2CH2OH]Cl. It is bifunctional, containing both quaternary ammonium salt and an alcohol. The cation is choline, which occurs naturally. It is a white, water-soluble salt used mainly in animal feed. It is an important additive in feed especially for chickens where it accelerates growth. It is also used as a clay control additive in fluids used for hydraulic fracturing.

Choline Chloride Dietary Supplement USP Grade Specifications:
C5H14ClNO --- 139.62
(2-Hydroxyethyl)trimethylammonium chloride;
2-Hydroxy-N,N,N-trimethylethanaminium chloride CAS 67-48-1

DEFINITION
Choline Chloride contains NLT 99.0% and NMT 100.5% of choline chloride (C5H14ClNO), calculated on the anhydrous basis.

IDENTIFICATION
A. Infrared Absorption
B. Identification Tests—General, Chloride: A solution (1 in 20) meets the requirements.

ASSAY
Procedure
Sample: 120 mg
Titrimetric system
Mode: Direct titration
Titrant: 0.1 N silver nitrate.
Endpoint detection: Potentiometric
Blank: 35 mL of water. Add 3 drops of acetic acid.
Analysis: Dissolve the Sample in 35 mL of water and add 3 drops of acetic acid. Titrate with Titrant.
Calculate the percentage of choline chloride (C5H14ClNO) in the Sample taken:
Result = [(V − B) × N × F × 100]/W
V = Sample titrant volume (mL)
B = Blank ;titrant volume (mL)
N = titrant normality (mEq/mL)
F = equivalency factor, 139.6 mg/mEq
W = weight of the Sample (mg)
Acceptance criteria: 99.0%–100.5% on the anhydrous basis.

Specifications of Choline Chloride FCC Food Grade
(2-Hydroxyethyl)trimethylammonium Chloride
HOCH2CH2N (CH3)3 Cl
C5H14ClNO Formula wt 139.65
INS: 1001(iii) CAS: [67-48-1]

DESCRIPTION
Choline Chloride occurs as colorless or white crystals or as a crystalline powder. It is hygroscopic, and is very soluble in water and in alcohol.
Function: Nutrient.

REQUIREMENTS
Identification:
A. A sample responds to Identification.
B. A 1:20 aqueous solution gives positive tests for Chloride.
Assay: Not less than 98.0% and not more than 100.5% of C5H14ClNO, calculated on the anhydrous basis.
1,4-Dioxane: Passes test.
Lead: Not more than 2 mg/kg.
Residue on Ignition: Not more than 0.05%.
Water: Not more than 0.5%.

Choline Chloride SDS Safety Data Sheet
MSDS, Material Safety Data Sheet 17-Jul-21

Product Name & Other Names: Choline Chloride or Ethanaminium of 2-hydroxy-N,N,N-trimethyl-chloride or biocolina or Hepacholine or Lipotril or Choline Chlorhydrate.
CAS No.: 67-48-1
EINECS EC Code: 200-655-4
Molecular Weight: 139.63
Chemical Formula: HOCH2CH2N (CH3)3HCl, C5H14ClNO
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: AS per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 5, H303
Skin irritation Category 2, H315
Eye irritation Category 2A, H319
Specific target organ toxicity – single exposure, Respiratory system Category 3, H335

Hazard statements:
H303: May be harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P 270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P362: Take off contaminated clothing and wash before reuse.
P501: Dispose of contents/container to authorised agents.

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
Notes to Physician: Treat symptomatically.

Fire: Choline chloride is not expected to be a significant fire hazard. It may be combustible at high temperatures.
Explosion: No information found.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, fog or carbon dioxide.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Dry material is solid and solution is liquid.
Odor: Odorless.
Odor threshold: Not available.
pH: is acidic around 6
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water
Viscosity: Not available.
Molecular Weight: 139.62
Molecular Formula: HOCH2CH2N (CH3)3HCl, C5H14ClNO

Stability: Choline chloride is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: May emit hydrogen chloride, chlorine, and oxides of nitrogen and carbon and toxic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents and extreme heat.
Conditions to Avoid: Incompatibles.

Oral rat LD50: 3400 mg/kg.
Oral mouse LD50: 3900 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose container and unused contents in accordance with law.

Domestic Land DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
International Water IMO/IMDG: Not Regulated.
International Air ICAO/IATA: Not Regulated.

USA:
SARA Section 302 Extremely Hazardous Substances: Does not have a TPQ.
California Proposition 65: Not listed.
SARA 311/312 Hazards: See section 2.

Choline Chloride Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals. Check.

Specifications, Properties, Uses, SDS of Choline Chloride USP Dietary Supplement and FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 67-48-1.

Choline Chloride Manufacturers, Suppliers, Exporters, Wholesalers: