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Specifications, Properties, Uses, SDS of Saccharin Sodium USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 82385-42-0 & 6155-57-3 for Dihydrate and 128-44-9 for Anhydrous. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Saccharin Sodium for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Saccharin Sodium CAS Number 82385-42-0 & 6155-57-3 for Dihydrate and 128-44-9 for Anhydrous
For Properties Specifications Uses of Saccharin Sodium Click Properties, Specifications, Uses, Price, Process of Saccharin Sodium Manufacturer.
For For SDS MSDS Sheet of Saccharin Sodium Click SDS Safety Data Sheet MSDS Sheet of Saccharin Sodium Manufacturer.
The Properties, Specifications, Monograph and Uses of Saccharin Sodium:
CAS Number: 82385-42-0 & 6155-57-3 for Dihydrate and 128-44-9 for Anhydrous, EINECS EC Number: 204-886-1, Molecular Formula: C7H4NNaO3S-xH2O, Molecular Weight: 205.17 (anhydrous), HS Code 29251100
Saccharin, sodium salt appears as odorless white crystals or crystalline powder. Aqueous solution is neutral or alkaline to litmus. It has intensely sweet taste. Sodium saccharin is the solid form of the artificial sweetener saccharin. Saccharin is non-nutritive and is used to add sweetness to beverages and foods without the calories or detrimental effects of consuming sugar. Using artificial sweeteners can help you reduce your consumption of sugar. Saccharin sodium salt is used in a variety of industry such as food and beverage, personal care products, table top sweetener, electroplating brighteners, pharmaceuticals etc.
Saccharin Sodium USP Grade Specifications:
C7H4NNaO3S-2H2O --- 241.20
C7H4NNaO3S --- 205.17
1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt, dihydrate;
1,2-Benzisothiazolin-3-one 1,1-dioxide sodium salt dihydrate CAS 6155-57-3
Anhydrous 128-44-9
DEFINITION
Saccharin Sodium contains NLT 99.0% and NMT 101.0% of saccharin sodium (C7H4NNaO3S), calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption
Sample: Dry at 105C to constant weight.
B. Procedure
Sample solution: 100 mg/mL
Potassium pyroantimonate solution: Dissolve 2 g of potassium pyroantimonate in 95 mL of hot water. Cool quickly and add 50 mL of a potassium hydroxide solution (50 mg/mL) and 1 mL of sodium hydroxide solution (8.5 in 100). Allow to stand for 24 h, filter, and dilute with water to 150 mL.
Analysis: To 10 mL of the Sample solution add 2 mL of 15% potassium carbonate, and heat to boiling. No precipitate is formed. Add 4 mL of Potassium pyroantimonate solution, and heat to boiling. Allow to cool in ice water and, if necessary, rub the inside of the test tube with a glass rod.
Acceptance criteria: A dense precipitate is formed.
C. Sodium salts impart an intense yellow color to a nonluminous flame.
ASSAY
Procedure
Sample solution: Dissolve 150 mg of Saccharin Sodium in 50 mL of glacial acetic acid. [Note: Slight heating may be needed to dissolve the sample.]
Analysis: Titrate the Sample solution with 0.1 N perchloric acid, determining the endpoint potentiometrically. Perform a blank determination and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 20.52 mg of saccharin sodium (C7H4NNaO3S).
Acceptance criteria: 99.0% to 101.0% on the anhydrous basis
o-Toluenesulfonamide: 10 ppm maximum.
p-Toluenesulfonamide: 10 ppm maximum.
Limit of Benzoate and Salicylate:
Sample solution: 50 mg/mL
Analysis: To 10 mL of the Sample solution add 5 drops of 6 N acetic acid, and then add 3 drops of ferric chloride.
Acceptance criteria: No precipitate or violet color appears.
Water Determination: NMT 15.0%
Readily Carbonizable Substances:
Matching fluid A: Cobaltous chloride CS, ferric chloride CS, cupric sulfate CS, and water (0.1: 0.4: 0.1: 4.4)
Sample solution: 40 mg/mL in sulfuric acid [94.5% to 95.5% (w/w) of H2SO4], maintained at 48C to 50C for 10 min.
Acceptance criteria: The Sample solution has no more color than Matching fluid A, when viewed against a white background.
Acidity or Alkalinity:
Sample solution: 100 mg/mL in carbon dioxide-free water
Analysis: To 10 mL of the Sample solution add 1 drop of phenolphthalein.
Acceptance criteria: No red or pink color is produced. Then add 1 drop of 0.1 N sodium hydroxide: a red or pink color is produced.
Clarity of Solution: To pass the test.
Color of Solution: To pass the test.
Packaging and Storage: Preserve in well-closed containers. Store at room temperature.
Specifications of Saccharin Sodium BP Ph Eur Grade
Soluble Saccharin
C7H4NNaO3S --- 205.2 --- CAS 128-44-9
Action and use: Sweetening agent.
DEFINITION
2-Sodio-1,2-benzisothiazol-3(2H)-one 1,1-dioxide.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance). It may contain a variable quantity of water.
CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals, efflorescent in dry air.
Solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent).
IDENTIFICATION
First identificationiB, E.
Second identificationiA, C, D, E.
A. Melting point: 226C to 230C.
To 5 ml of solution S (see Tests) add 3 ml of dilute hydrochloric acid. A white precipitate is formed. Filter and wash with water. Dry the precipitate at 100C to 105C.
B. Infrared absorption spectrophotometry.
C. Mix about 10 mg with about 10 mg of resorcinol, add 0.25 ml of sulphuric acid and carefully heat the mixture over a naked flame until a dark green colour is produced. Allow to cool, add 10 ml of water and dilute sodium hydroxide solution until an alkaline reaction is produced. An intense green fluorescence develops.
D. To 0.2 g add 1.5 ml of dilute sodium hydroxide solution, evaporate to dryness and heat the residue carefully until it melts, avoiding carbonisation. Allow to cool, dissolve the mass in about 5 ml of water, add dilute hydrochloric acid until a weak acid reaction is produced and filter, if necessary. To the filtrate add 0.2 ml of ferric chloride solution. A violet colour develops.
E. Solution S gives reaction (a) of sodium.
TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water and dilute to 50.0 ml with the same solvent.
Appearance of solution: The solution is clear and colourless.
Dissolve 5.0 g in 25 ml of carbon dioxide-free water.
Acidity or alkalinity: To 10 ml of solution S add about 0.05 ml of a 10 g/l solution of PhPh in ethanol (96 per cent). The solution is not pink. Add 0.1 ml of sodium hydroxide 0.1 M. The solution becomes pink.
o- and p-Toluenesulphonamide: Gas chromatography to pass the test.
Readily carbonisable substances: Dissolve 0.20 g in 5 ml of sulphuric acid and keep at 48C to 50C for 10 min. When viewed against a white background, the solution is not more intensely coloured than a solution prepared by mixing 0.1 ml of red primary solution, 0.1 ml of blue primary solution and 0.4 ml of yellow primary solution with 4.4 ml of water.
Heavy metals: Maximum 20 ppm.
Water: Maximum 15.0 per cent, determined on 0.200 g.
ASSAY
Dissolve 0.150 g in 50 ml of anhydrous acetic acid, with slight heating if necessary. Titrate with 0.1 M perchloric acid, determining the end-point potentiometrically. Carry out a blank titration. 1 ml of 0.1 M perchloric acid is equivalent to 20.52 mg of C7H4NNaO3S.
In an airtight container.
Specifications of Sodium Saccharin FCC Food Grade
1,2-Benzisothiazole-3(2H)-one 1,1-Dioxide Sodium Salt;
Sodium o-Benzosulfimide; Soluble Saccharin
C7H4NNaO3S·2H2O --- Formula weight 241.19
INS: 954 CAS: 128-44-9
DESCRIPTION
Sodium Saccharin occurs as white crystals or as a white, crystalline powder. In powdered form, it effloresces to the extent that it usually contains only about one-third the amount of water indicated in its molecular formula. One gram is soluble in 1.5 mL of water and in about 50 mL of alcohol.
Function: Nonnutritive sweetener.
Identification:
A. Dissolve about 100 mg of sample in 5 mL of a 1:20 solution of sodium hydroxide, evaporate to dryness, and gently fuse the residue over a small flame until ammonia no longer evolves. After the residue has cooled, dissolve it in 20 mL of water, neutralize the solution with 2.7 N hydrochloric acid, and filter. Add 1 drop of ferric chloride to the filtrate. A violet color appears.
B. Mix 20 mg of sample with 40 mg of resorcinol, cautiously add 10 drops of sulfuric acid, and heat the mixture in a liquid bath at 200C for 3 min. After cooling, add 10 mL of water and an excess of 1 N sodium hydroxide. A fluorescent green liquid results.
C. The residue obtained by igniting a 2-g sample gives positive tests for Sodium.
D. Add 1 mL of hydrochloric acid to 10 mL of a 1:10 aqueous solution. A crystalline precipitate of saccharin forms. Wash the precipitate well with cold water, and dry at 105C for 2 h. The saccharin thus obtained melts between 226C and 230C.
Assay: Not less than 98.0% and not more than 101.0% of C7H4NNaO3S, calculated on the anhydrous basis.
Alkalinity: Passes test.
Benzoate and Salicylate: Passes test.
Lead: Not more than 2 mg/kg.
Readily Carbonizable: Substances Passes test.
Selenium: Not more than 0.003%.
Toluenesulfonamides: Not more than 0.0025%.
Water: Not more than 15.0%.
The MSDS-SDS Hazard Statement of Saccharin Sodium:
Sodium Saccharin SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 24-Jul-21
1. PRODUCT DESCRIPTION
Product Name & Other Names: Sodium Saccharin.
CAS Number: 82385-42-0
EINECS EC Number: 204-886-1
Molecular Weight: 205.17 (anhydrous)
Molecular Formula: C7H4NNaO3S-xH2O
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. HAZARD IDENTIFICATION
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
| GHS Label Elements None |
Signal Words: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product Name & Other Names: Sodium Saccharin.
CAS Number: 82385-42-0
EINECS EC Number: 204-886-1
4. FIRST AID MEASURES
Always get medical attention after the first aid is over.
Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If Sodium Saccharin is swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.
5. FIREFIGHTING PROCEDURES
Extinguisher Media: Water spray. Carbon dioxide (CO 2). Dry chemical. alcohol-resistant foam.
Flammable Limits in Air % by Volume: N/A
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. SPILL OR LEAK PROCEDURES
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. SPECIAL PRECAUTIONS
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. SPECIAL PROTECTION INFORMATION
Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. Better keep it under 10 mg/m3
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. PHYSICAL DATA
Appearance: White Crystalline Powder or Granules.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water
Viscosity: Not available.
Molecular Weight: 205.17 (anhydrous)
Molecular Formula: C7H4NNaO3S-xH2O
10. REACTIVITY DATA
Stability: Stable under normal conditions.
Conditions to Avoid: Heat and Strong oxidizing agents.
Incompatibility (Materials to Avoid): Strong oxidizing.
Hazardous Decomposition Products: Carbon oxides, Nitrogen oxides (NOx), Sulphur oxides, Sodium oxide.
Hazardous Polymerization: Will not occur
11. TOXICITY DATA
LD50 Oral - Rat - 14,200 mg/kg
Carcinogenicity: No product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by NTP, ACGIH & OSHA. It is a Group 3: Not classifiable as to its carcinogenicity to humans as per IARC.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. ECOLOGICAL DATA
Toxicity to fish: No information available.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. DISPOSAL INFORMATION
Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations.
14. TRANSPORT INFORMATION
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
Sea Transport IMDG/IMO: Not regulated.
Air Transport IATA/ICAO: Not regulated.
15. REGULATORY INFORMATION
USA:
SARA 311/312 Hazards: No SARA Hazards. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
16. ADDITIONAL INFORMATION
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Saccharin Sodium Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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