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Specifications, Properties, Uses, SDS of Resorcinol USP BP Ph Eur Analytical Reagent Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 108-46-3.
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Resorcinol CAS Number 108-46-3For Properties Specifications Uses of Resorcinol Click Properties, Specifications, Uses, Price, Process of Resorcinol Manufacturer.
For For SDS MSDS Sheet of Resorcinol Click SDS Safety Data Sheet MSDS Sheet of Resorcinol Manufacturer.
The Properties, Specifications, Monograph and Uses of Resorcinol:
CAS Number: 108-46-3, EINECS EC Number: 203-585-2, Molecular Formula: C6H4-1,3-(OH)2, Molecular Weight: 110.11, HS Code 29072100
Resorcinol is a very white crystalline solid that becomes pink on exposure to light. Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. Resorcinol is used in the production of resins. As a mixture with phenol, it condenses with formaldehyde to afford adhesives. It is present in over-the-counter topical acne medicine.
Resorcinol USP Grade Specifications:
C6H6O2 --- 110.11
1,3-Benzenediol
Resorcinol CAS 108-46-3Resorcinol contains not less than 99.0 percent and not more than 100.5 percent of C6H6O2, calculated on the dried basis.
Packaging and storage: Preserve in well-closed, light-resistant containers.
Identification:
A: Infrared Absorption: [note: If necessary to recrystallize, dissolve in dehydrated alcohol.]
B: Dissolve 100 mg in 2 mL of 1 N sodium hydroxide, add 1 drop of chloroform, and heat the mixture: an intense crimson color is produced. Then add a slight excess of hydrochloric acid: the color changes to pale yellow.
C: To 10 mL of a solution (1 in 100) add 1 drop of ferric chloride: a blue-violet color is produced, and it fades slowly.Melting range: between 109C and 111C.
Assay: Dissolve about 1.5 g of Resorcinol, accurately weighed, in water to make 500.0 mL. Transfer to an iodine flask 25.0 mL of the resulting solution, add 50.0 mL of 0.1 N bromine, dilute with 50 mL of water, add 5 mL of hydrochloric acid, and at once insert the stopper in the flask. Shake for 1 minute, allow to stand for 2 minutes, and add 10 mL of potassium iodide while slightly loosening the stopper. Shake thoroughly, allow to stand for 5 minutes, remove the stopper, and rinse it and the neck of the flask with 20 mL of water into the flask. Titrate the liberated iodine with 0.1 N sodium thiosulfate, adding starch as the endpoint is approached. Perform a blank determination. From the volume of 0.1 N sodium thiosulfate used, calculate the volume, in mL, of 0.1 N bromine consumed by the resorcinol. Each mL of 0.1 N bromine is equivalent to 1.835 mg of C6H6O2.
Loss on drying: Dry it over silica gel for 4 hours: it loses not more than 1.0% of its weight.
Residue on ignition: not more than 0.05%.
Phenol: Heat gently a solution (1 in 20): the odor of phenol is not perceptible.
Catechol: To 10 mL of a solution (1 in 20) previously mixed with 2 drops of 1 N acetic acid add 0.5 mL of lead acetate: no turbidity is produced.
Ordinary impurities: To pass the test.
Limits: not more than 1.0%.
Resorcinol BP Grade
Ph Eur
C6H6O2 --- 110.1 --- CAS 108-46-3Action and use: Keratolytic.
DEFINITION
Resorcinol contains not less than 98.5 per cent and not more than the equivalent of 101.0 per cent of benzene-1,3-diol, calculated with reference to the dried substance.CHARACTERS
A colourless or slightly pinkish-grey, crystalline powder or crystals, turning red on exposure to light and air, very soluble in water and in alcohol.IDENTIFICATION
A. Melting point:109C to 112C.
B. Dissolve 0.1 g in 1 ml of water add 1 ml of strong sodium hydroxide solution and 0.1 ml of chloroform, heat and allow to cool. An intense, deep-red colour develops which becomes pale yellow on the addition of a slight excess of hydrochloric acid.
C. Thoroughly mix about 10 mg with about 10 mg of potassium hydrogen phthalate, both finely powdered. Heat over a naked flame until an orange-yellow colour is obtained. Cool and add 1 ml of dilute sodium hydroxide solution and 10 ml of water and shake to dissolve. The solution shows an intense green fluorescence.TESTS
Solution S: Dissolve 2.5 g in carbon dioxide-free water R and dilute to 25 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution and remains so when heated in a water-bath for 5 min.
Acidity or alkalinity: To 10 ml of solution S add 0.05 ml of bromophenol blue solution. Not more than 0.05 ml of 0.1 M hydrochloric acid or 0.1 M sodium hydroxide is required to change the colour of the indicator.
Related substances: To pass the test
Pyrocatechol: To 2 ml of solution S add 1 ml of ammonium molybdate solution and mix. Any yellow colour in the solution is not more intense than that in a standard prepared at the same time in the same manner using 2 ml of a 0.1 g/l solution of pyrocatechol.
Loss on drying: Not more than 1.0 per cent, determined on 1.00 g of powdered substance by drying in a desiccator for 4 h.
Sulphated ash: Not more than 0.1 per cent, determined on 1.0 g.
1,3-Benzenediol or Resorcinol Analytical Reagent Grade
1,3-C6H4(OH)2
Formula Wt 110.11
CAS Number 108-46-3REQUIREMENTS
Assay: 99.0-100.5% C6H4(OH)2
Melting point: 110-112C.
The MSDS-SDS Hazard Statement of Resorcinol:
Resorcinol SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 24-Jul-211. Product Identification
Product Name & Other Names: Resorcinol.
CAS No.: 108-46-3
EINECS EC Number: 203-585-2
Molecular Weight: 110.11
Chemical Formula: C6H4-1,3-(OH)2
Relevant uses and uses advised against (if any): Industrial use only
Supplier: As per letterhead.2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Eye damage (Category 1), H318
Hazardous to the aquatic environment, acute hazard (Category 1) H400Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements
IrritantGHS Label Elements
Marine PollutantSignal Words: Warning
Hazard statements:
H302 Harmful if swallowed.
H315 Causes skin irritation.
H318 Causes serious eye damage.
H400 Very toxic to aquatic life.Precautionary statements:
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P314 Get Medical advice/attention if you feel unwell.
P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P305+ P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P330 Rinse mouth.
P360 Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P501 Dispose of contents/ container to an approved waste disposal plant.3. Composition/Information on Ingredients
Product Name & Other Names: Resorcinol
CAS No.: 108-46-3
EINECS EC Number: 203-585-24. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.5. Fire Fighting Measures
Fire: Combustible.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Water spray, alcohol-resistant foam, dry chemical, or carbon dioxide may be used to keep fire exposed containers cool.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, iron, and iron salts. Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing.8. Exposure Controls/Personal Protection
Airborne Exposure Limits: TWA 10 ppm USA. ACGIH Threshold Limit Values (TLV)
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a half face piece particulate respirator (NIOSH type N95 or better filters) may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest.. A full-face piece particulate respirator may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.9. Physical and Chemical Properties
Physical state and appearance: White Solid.
Odor: Typical.
Odor threshold: Not available.
pH: 4-6
Relative density: around 1.28
Initial Boiling Point: 178C literature.
Melting Point: 109C - 112C
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Not available.
Viscosity: Not available.
Molecular Weight: 110.11
Chemical Formula: C6H4-1,3-(OH)210. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Involvement in a fire causes decomposition to form oxides of carbon and fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents, Iron and iron salts.
Conditions to Avoid: Heat, moisture, incompatibles.11. Toxicological Information
TOXICITY DATA:
LD50: 301 Mg/Kg (Rat)
LD50 Rabbit: 3,360 mg/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.12. Ecological Information
Toxicity to fish: flow-through test LC50 - Pimephales promelas (fathead minnow) - 29.5 mg/l - 96 h
Toxicity to daphnia and other aquatic invertebrates: semi-static test EC50 - Daphnia magna (Water flea) - 1 mg/l - 48 h
Biological effects: Highly toxic for aquatic organisms.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with legal requirements.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe
UN number: 2876
Class: 6.1
Packing group: III
Proper shipping name: Resorcinol
Sea Transport IMO/IMDG
UN number: 2876
Class: 6.1
Packing group: III
Proper shipping name: Resorcinol
Air Transport IATA
UN number: 2876
Class: 6.1
Packing group: III
Proper shipping name: Resorcinol.15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Resorcinol Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564e-mail: info@kingofchemicals.com
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