Specifications, SDS of Magnesium Sulfate Heptahydrate Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Magnesium Sulfate Heptahydrate USP BP Ph Eur IP Reagent FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 10034-99-8.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Magnesium Sulfate Heptahydrate for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

The Properties, Specifications, Monograph and Uses of Magnesium Sulfate Heptahydrate:

Molecular Weight 246.48, CAS Number 10034-99-8, EINECS 231-298-2, HS Code: 28332100, Chemical Formula MgSO4-7H2O

Magnesium sulfate or Magnesium sulphate is a magnesium salt having sulfate as the counterion. It has a role as an anticonvulsant, a cardiovascular drug, a calcium channel blocker, an anaesthetic, a tocolytic agent, an anti-arrhythmia drug, an analgesic and a fertilizer. It is a magnesium salt and a metal sulfate. It is asmall colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. The most common is the heptahydrate MgSO4-7H2O, known as Epsom salt, which is a household chemical with many traditional uses, including bath salts. The heptahydrate takes its common name "Epsom salt" from a bitter saline spring in Epsom in Surrey, England, where the salt was produced from the springs.

Specifications of Magnesium Sulfate Heptahydrate:
Appearance: Fine, white, sparkling crystal, free flowing
Molecular formula: MgSO4-7H2O
Solubility: Readily soluble in water
Purity as (MgSO4-7H2O ): 99% minimum.
Magnesium oxide as (MgO): 16.20% minimum.
Magnesium as (Mg): 9.70% minimum.
Sulphur as (SO4): 38.60% minimum.
pH of 5% aqueous solution: 7 + / - 0.5
Chlorides as (Cl) % by mass: 0.012 % maximum.
Heavy metals as (Pb): not detectable.
Arsenic as (As2O3):less than 1.00 ppm maximum.
Iron as (Fe): 10 ppm maximum.
Manganese as (Mn): 15 ppm maximum.

Specifications of Magnesium Sulfate USP Grade
MgSO4-xH2O
Sulfuric acid magnesium salt (1:1), hydrate.
Magnesium sulfate (1:1) monohydrate 138.36
Magnesium sulfate (1:1) heptahydrate 246.48 CAS 10034-99-8.
Anhydrous 120.37 CAS 7487-88-9.

Magnesium Sulfate, rendered anhydrous by ignition, contains not less than 99.0 percent and not more than 100.5 percent of MgSO4.

Identification: A solution (1 in 20) responds to the tests for Magnesium and for Sulfate.
pH: between 5.0 and 9.2, in a solution (1 in 20).
Loss on drying: Dry it at 105 for 2 hours: the anhydrous form loses not more than 2% of its weight.
Loss on ignition: Weigh accurately about 1 g in a crucible, heat at 105 for 2 hours, then ignite in a muffle furnace at 450±25C to constant weight: the monohydrate loses between 13.0% and 16.0% of its weight, the dried form loses between 22.0% and 28.0% of its weight, and the heptahydrate loses between 40.0% and 52.0% of its weight.
Chloride: A 1.0-g portion shows no more chloride than corresponds to 0.20 mL of 0.020 N hydrochloric acid (0.014%).
Iron:
For magnesium sulfate intended for use in preparing non-parenteral dosage forms: Dissolve 0.50 g in 40 mL of water and proceed as directed in the test for Iron: the limit is 20µg per g.
For magnesium sulfate intended for use in preparing parenteral dosage forms: the limit is 0.5µg per g.
Heavy metals: Dissolve 2 g in 25 mL of water: the limit is 0.001%.
Selenium: The limit is 0.003%.

Specifications of Dried Magnesium Sulphate BP Ph Eur Magnesium Sulfate
Dried Epsom Salts
Preparation: Magnesium Sulphate Paste

DEFINITION
Dried Magnesium Sulphate contains not less than 62.0% and not more than 70.0% of MgSO4.
It may be prepared by drying magnesium sulphate at 100° until it has lost approximately 25% of its weight.

CHARACTERISTICS
A white powder. Freely soluble in water; dissolves more rapidly in hot water.

IDENTIFICATION
Yields the reactions characteristic of magnesium salts and of sulphates.

TESTS
Acidity or alkalinity: To 10 ml of a 7.5% w/v solution in carbon dioxide-free water add 0.05 ml of phenol red solution. Not more than 0.2 ml of either 0.01M hydrochloric acid or 0.01M sodium hydroxide is required to change the colour of the solution.
Arsenic: 0.33 g dissolved in 25 ml of water complies with the limit test for arsenic, (3 ppm).
Heavy metals: Dissolve 1.3 g in 20 ml of water and add 1 g of ammonium chloride. 12 ml of the resulting solution complies with limit test A for heavy metals, Appendix VII. Use lead standard solution(1 ppm Pb) to prepare the standard (15 ppm).
Iron: 0.33 g dissolved in 10 ml of water complies with the limit test for iron, Appendix VII (30 ppm).
Chloride: 0.13 g dissolved in 15 ml of water complies with the limit test for chlorides, Appendix VII (400 ppm).
Insoluble matter: 7.5 g dissolves in 20 ml of water, producing a solution which may be slightly turbid at first but which becomes clear in a few minutes.

Specifications of Magnesium Sulphate Heptahydrate BP
Epsom Salts
MgSO4-7H2O --- 246.5 --- 10034-99-8
Action and use: Osmotic laxative; used in treatment of electrolyte deficiency.

CHARACTERS
Appearance: White or almost white, crystalline powder or brilliant, colourless crystals.
Solubility: Freely soluble in water, very soluble in boiling water, practically insoluble in ethanol (96 per cent).

IDENTIFICATION
A. It gives the reactions of sulphates.
B. It gives the reaction of magnesium.

TESTS
Solution S: Dissolve 5.0 g in water R and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 10 ml of solution S add 0.05 ml of phenol red solution. Not more than 0.2 ml of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Chlorides: Maximum 300 ppm.
Arsenic: Maximum 2 ppm, determined on 0.5 g.
Iron: Maximum 20 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: 48.0 per cent to 52.0 per cent, determined on 0.500 g by drying in an oven at 110-120C for 1 h and then at 400C to constant mass.

Specifications of Magnesium Sulfate FCC Food Grade Magnesium Sulphate
Epsom Salt
MgSO4-xH2O Formula weight, monohydrate 138.38
Formula wt, heptahydrate 246.47
INS: 518 CAS: monohydrate CAS 14168-73-1
CAS: heptahydrate CAS 10034-99-8
CAS: dried CAS 15244-36-7
Magnesium Sulphate Dried is offered in FCC grade

DESCRIPTION
Magnesium Sulfate occurs as a colorless crystal or a granular crystalline powder. It is produced with one or seven molecules of water of hydration or in a dried form containing the equivalent of about 2.3 waters of hydration. It is readily soluble in water, slowly soluble in glycerin, and sparingly soluble in alcohol.
Function: Nutrient.

REQUIREMENTS
Identification: A 1:20 aqueous solution gives positive tests for Magnesium and for Sulfate.
Assay: Not less than 99.5% of MgSO4 after ignition.
Lead: Not more than 4 mg/kg.
Loss on Ignition Monohydrate: Between 13.0% and 16.0%; Heptahydrate: Between 40.0% and 52.0%; Dried: Between 22.0% and 28.0%.
Selenium: Not more than 0.003%.

Specifications of Magnesium Sulfate Analytical Reagent Magnesium Sulphate
Magnesium Sulfate Heptahydrate
MgSO4-7H2O
Formula Weight 246.48
CAS Number 10034-99-8

REQUIREMENTS
Assay: 98.0-102.0% MgSO4-7H2O
pH of a 5% solution: 5.0-8.2 at 25C

MAXIMUM ALLOWABLE
Insoluble matter: 0.005%
Chloride (Cl): 5 ppm
Nitrate (NO3): 0.002%
Ammonium (NH4): 0.002%
Calcium (Ca): 0.02%
Manganese (Mn): 5 ppm
Potassium (K): 0.005%
Sodium (Na): 0.005%
Strontium (Sr): 0.005%
Heavy metals (as Pb) 5 ppm
Iron (Fe): 5 ppm.

We also manufacture Micro-Encapsulated Magnesium Sulfate, having core of Magnesium Sulfate and coating of vegetable oil or mono and diglycerides or as desired by the buyer. Such encapsulation makes the product slow release or extended release.

Magnesium Sulfate Heptahydrate or Magnesium Sulphate Heptahydrate
SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 01-Jul-21

Product Name & Other Names: Magnesium sulphate heptahydrate or Magnesium sulfate (1:1) heptahydrate or Epsom salts or sulfuric acid magnesium salt (1:1) heptahydrate or Magnesium sulfate 7- hydrate.
CAS No.: 10034-99-8 Heptahydrate
EINECS: 231-298-2
Molecular Weight: 246.48
Chemical Formula: MgSO4-7H2O
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary Statements
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Inhalation: Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion: Give several glasses of water to drink to dilute. If large amounts were swallowed, get medical advice.
Skin Contact: Remove any contaminated clothing. Wash skin with soap and water for at least 15 minutes. Get medical attention if irritation develops or persists.
Eye Contact: Wash thoroughly with running water. Get medical advice if irritation develops.
Note to Physician: IV administration of calcium gluconate will partially reverse the effects of acute magnesium toxicity. Ventricular support with calcium chloride infusion and mannitol forced diuresis has also been successful.

Fire: Not flammable.
Explosion: It is not considered to be an explosion hazard.
Products of Combustion: Sulphuric acid, Sulphur Dioxide and Magnesium Oxide may be formed.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: None specified.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Contain spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating through the sanitary system if local laws permit.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, ethoxy ethyl alcohols, arsenates, phosphates, tartrates, lead, barium, strontium, and calcium.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White crystals or powder.
Odor: It is odorless.
Odor threshold: Not available.
pH: Aqueous solution is neutral or slightly acid.
Relative density: around 2.66
Melting Point: Loses water on heating.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Very soluble in water.
Viscosity: Not available.
Molecular Weight: 246.48
Molecular Formula: MgSO4-7H2O

Stability: Stable under ordinary conditions of use and storage. Absorbs moisture on exposure.
Hazardous Decomposition Products: Oxides of sulfur and the contained metal.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, Ethoxy ethyl alcohols, arsenates, phosphates, tartrates, lead, barium, strontium, and calcium.
Conditions to Avoid: Heat, moisture, incompatibles.

Toxicity to Animals:
D50 = No information found.
LC50 = No information found.
Carcinogenic Effects: No.
Mutagenic Effects: Laboratory experiments have resulted in mutagenic effects.
Teratogenic Effects: No.
Developmental Toxicity: Laboratory experiments have resulted in mutagenic effects.

Environmental Toxicity:
24 hour EC50 Daphnia magna (water flea) : 1700 mg/L.
24 hour LC50 Lepomis machrochirus (bluegill) : > 5000 mg/L [static].
72 hour EC50 Scenedesmus subspicatus (green algae) : 2700 mg/L.
This material is not expected to be toxic to aquatic life.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with legal requirements.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
Sea Transport IMDG/IMO: Not Regulated.
Air Transport IATA/ICAO: Not Regulated.

USA:
SARA Codes: See section 2.
Section 313: No chemicals are reportable under Section 313.

Magnesium Sulfate Heptahydrate Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Magnesium Sulfate Heptahydrate USP BP Ph Eur IP Reagent FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 10034-99-8.

Magnesium Sulfate Heptahydrate Manufacturers, Suppliers, Exporters, Wholesalers: