Specifications, Uses, SDS of Calcium Glycerophosphate Manufacturers

	King of Chemicals
Specifications, Properties, Uses, SDS of Calcium Glycerophosphate USP Dietary Supplement BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 27214-00-2.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Calcium Glycerophosphate for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

The Properties, Specifications, Monograph and Uses of Calcium Glycerophosphate:

CAS Number: 27214-00-2, EINECS EC Number: 248-328-5, Molecular Formula: C3H7CaO6P, Molecular Weight: 210.13 HS Code 29199020

Calcium glycerophosphate is an used to treat low levels of phosphate or calcium, as well as an ingredient in dental products to prevent dental caries. Calcium glycerophosphate is a Calcium salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings, and fillings. Calcium glycerylphosphate or calcium glycerophosphate) is a mineral supplement. Formerly it was sold as a nerve tonic. It is added to some kinds of toothpaste. Studies have found that calcium glycerophosphate can significantly reduce the urge to urinate, as well as minimize discomfort experienced after consuming highly acidic foods and beverages.

Specifications of Calcium Glycerophosphate BP Ph Eur
Ph Eur
C3H7CaO6P -- 210.1 -- 27214-00-2
Action and use: Excipient.

DEFINITION
Mixture in variable proportions of the calcium salt of 2,3-dihydroxypropyl phosphate and of 2-hydroxy-1-(hydroxymethyl)ethyl phosphate which may be hydrated.
Content: 18.6 per cent to 19.4 per cent of Ca (dried substance).

CHARACTERS
Appearance: White or almost white powder, hygroscopic.
Solubility: Sparingly soluble in water, practically insoluble in ethanol (96 per cent).

IDENTIFICATION
A. Mix 1 g with 1 g of potassium hydrogen sulphate in a test tube fitted with a glass tube.Heat strongly and direct the white vapour towards a piece of filter paper impregnated with a freshly prepared 10 g/l solution of sodium nitroprusside. The filter paper develops a blue colour in contact with piperidine.
B. Ignite 0.1 g in a crucible. Take up the residue with 5 ml of nitric acid and heat on a water-bath for 1 min. Filter. The filtrate gives reaction of phosphates.
C. It gives reaction of calcium.

TESTS
Solution S: Dissolve 1.5 g at room temperature in carbon dioxide-free water prepared from distilled water and dilute to 150 ml with the same solvent.
Appearance of solution: Solution S is not more opalescent than reference suspension.
Acidity or alkalinity: To 100 ml of solution S add 0.1 ml of phph solution. Not more than 1.5 ml of 0.1 M hydrochloric acid or 0.5 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator.
Citric acid: Shake 5.0 g with 20 ml of carbon dioxide-free water and filter. To the filtrate add 0.15 ml of sulphuric acid and filter again. To the filtrate add 5 ml of mercuric sulphate solution and heat to boiling. Add 0.5 ml of a 3.2 g/l solution of potassium permanganate and again heat to boiling. No precipitate is formed.
Glycerol and ethanol (96 per cent)-soluble substances: Maximum 0.5 per cent. Shake 1.000 g with 25 ml of ethanol (96 per cent) for 1 min. Filter. Evaporate the filtrate on a water-bath and dry the residue at 70C for 1 h. The residue weighs a maximum of 5 mg.
Chlorides: Maximum 500 ppm.
Phosphates: Maximum 400 ppm.
Sulphates: Maximum 0.1 per cent, determined on solution S.
Arsenic: Maximum 3 ppm.
Iron: Maximum 50 ppm, determined on 0.20 g.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 12.0 per cent, determined on 1.000 g by drying in an oven at 150C for 4 h.

Specifications of Calcium Glycerophosphate USP Dietary Supplement Grade:
C3H7CaO6P --- 210.14
1,2,3-Propanetriol, mono(dihydrogen phosphate) calcium salt (1:1);
Calcium glycerophosphate CAS 27214-00-2.

DEFINITION
Calcium Glycerophosphate is a mixture, in variable proportions, of calcium (RS)-2,3-dihydroxypropyl phosphate and calcium 2-hydroxy-1-(hydroxymethyl)ethyl phosphate, which may be hydrated. Calcium Glycerophosphate contains NLT 18.6% and NMT 19.4% of calcium (Ca), calculated on the dried basis.

IDENTIFICATION
A.
Analysis: Ignite 0.1 g in a crucible. Take up the residue with 5 mL of nitric acid, heat on a water bath for 1 min, and filter. Mix 1 mL of the filtrate with 2 mL of ammonium molybdate.
Acceptance criteria: A yellow color develops.
B.
Analysis: Dissolve 20 mg of the substance being examined in 5 mL of 5 M acetic acid and add 0.5 mL of potassium ferrocyanide solution (53 mg/mL). The resulting solution remains clear. To the clear solution, add 50 mg of ammonium chloride.
Acceptance criteria: A white crystalline precipitate is produced.

Specifications of Calcium Glycerophosphate FCC Food Grade
C3H7CaO6P Formula wt 210.14
CAS: 27214-00-2

DESCRIPTION
Calcium Glycerophosphate occurs as a fine, white powder. It is somewhat hygroscopic. One gram dissolves in about 50 mL of water at 25C. It is more soluble in water at a lower temperature, and citric acid increases its solubility in water. It is insoluble in alcohol.
Function: Nutrient.

REQUIREMENTS
Identification: A saturated sample solution gives positive tests for Calcium.
Assay: Not less than 98.0% and not more than 100.5% of C3H7CaO6P, after drying.
Alkalinity: Passes test.
Lead: Not more than 4 mg/kg.
Loss on Drying: Not more than 12.0%.

Calcium Glycerophosphate SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 26-Jun-21

Product Name & Other Names: Calcium Glycerophosphate or Glycerol phosphate calcium salt.
CAS No.: 27214-00-2
EINECS EC Number: 248-328-5
Molecular Weight: 210.13
Chemical Formula: C3H7CaO6P
Relevant uses and uses advised against (if any): Laboratory and Industrial Manufacturing Use.
SUPPLIER: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Calcium Glycerophosphate or Glycerol phosphate calcium salt.
CAS No.: 27214-00-2
EINECS EC Number: 248-328-5

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Not expected to require first aid measures. If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact: Not expected to require first aid measures. Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.

Fire: It is not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White solid or crystals or powder.
Odor: Odorless.
Odor threshold: Not available.
pH: about 8.
Relative density: Not available.
Boiling Point: Decomposes.
Melting Point: Decomposes at red heat.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 210.13
Chemical Formula: C3H7CaO6P

Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon oxides, Oxides of phosphorus, Calcium oxide.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents and Heat.
Conditions to Avoid: Excessive dust generation.

Acute toxicity: LD50 (oral, Rat): >5000 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

Environmental Toxicity: Not much found.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with federal, state, and local requirements.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport TDG/IMDG: Not dangerous goods.
Air Transport ICAO/IATA: Not dangerous goods.

Calcium Glycerophosphate Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Calcium Glycerophosphate USP Dietary Supplement BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 27214-00-2.

Calcium Glycerophosphate Manufacturers, Suppliers, Exporters, Wholesalers: