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Specifications, Properties, Uses, SDS of Coated Activated Precipitated Calcium Carbonate USP BP Ph Eur Reagent FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 471-34-1. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Coated Activated Precipitated Calcium Carbonate for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Coated Activated Precipitated Calcium Carbonate CAS Number 471-34-1
For Properties Specifications Uses of Coated Activated Precipitated Calcium Carbonate Click Properties, Specifications, Uses, Price, Process of Coated Activated Precipitated Calcium Carbonate Manufacturer.
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The Properties, Specifications, Monograph and Uses of Coated Activated Precipitated Calcium Carbonate:
CAS Number: 471-34-1, Molecular Weight: 100.09, Chemical Formula: CaCO3 EINECS EC Number: 207-439-9, HS Code 28365000
Calcium carbonate is a chemical compound with the formula CaCO3. It is a common substance found in rocks as the minerals calcite and aragonite (most notably as limestone. Refined Calcium Carbonate is precipitated from other purer calcium containing chemicals. It has medical use as a calcium supplement, as an excipiet and as an antacid. As a food additive it is designated E-number of E170 and it has an INS number of 170. Used as an acidity regulator, anticaking agent, stabilizer or color it is approved for usage in the EU USA, Australia and New Zealand. Calcium carbonate is a dietary supplement used when the amount of calcium taken in the diet is not enough. Calcium is needed by the body for healthy bones, muscles, nervous system, and heart. Calcium carbonate also is used as an antacid to relieve heartburn, acid indigestion, and upset stomach. It is available with or without a prescription.
Calcium Carbonate USP Grade Specifications:
CaCO3 --- 100.09
Carbonic acid, calcium salt (1:1);
Calcium carbonate (1:1) --- CAS 471-34-1
DEFINITION
Calcium Carbonate, dried at 200C for 4 h, contains calcium equivalent to NLT 98.0% and NMT 100.5% of calcium carbonate (CaCO3).
IDENTIFICATION
A. Identification Tests - General, Calcium: The addition of acetic acid to it produces effervescence (presence of carbonate), and the resulting solution, after boiling, meets the requirements of the tests.
ASSAY
Titrimetry:
Sample: 200 mg of Calcium Carbonate, previously dried at 200C for 4 h
Blank: 100 mL of water and 15 mL of 1 N sodium hydroxide
Titrimetric system
Mode: Direct titration
Titrant: 0.05 M edetate disodium
Indicator: 300 mg of hydroxy naphthol blue
Endpoint detection: Visual, change to distinct blue
Analysis: Transfer the Sample to a 250-mL beaker. Moisten thoroughly with a few mL of water, and add, dropwise, sufficient 3 N hydrochloric acid to dissolve. Add 100 mL of water, 15 mL of 1 N sodium hydroxide, and 300 mg of hydroxy naphthol blue. Titrate with the Titrant. Calculate the percentage of calcium carbonate (CaCO3) in the Sample taken:
Result = [(V - B) x M x F x 100]/W
V = Sample titrant volume (mL)
B = Blank titrant volume (mL)
M = titrant molarity (mmol/mL)
F = equivalency factor, 100.09 mg/mmol
W = weight of the Sample (mg)
Acceptance criteria: 98.0% to 100.5% on the dried basis
Sample: 5.0 g
Analysis: Mix the Sample with 10 mL of water, and add hydrochloric acid, dropwise, with agitation, until it ceases to cause effervescence, then add water to make the mixture measure 200 mL, and filter. Wash the insoluble residue with water until the last washing shows no chloride and ignite and weigh the residue.
Acceptance criteria: NMT 0.2%; the weight of the residue does not exceed 10 mg.
Arsenic: To pass the test. NMT 3 ppm
Barium: A platinum wire, dipped in the filtrate obtained in the test for Acid-Insoluble Substances and held in a nonluminous flame, does not impart a green color.
Iron: To pass the test by Ultraviolet-Visible Spectroscopy.
Lead:
Sample solution: 1.0 g in 5 mL of water
Analysis: To the Sample solution slowly add 8 mL of 3 N hydrochloric acid, evaporate on a steam bath to dryness, and dissolve the residue in 5 mL of water.
Acceptance criteria: NMT 3 ppm
Limit of Fluoride: To pass the test.
Acceptance criteria: NMT 50 ppm
Limit of Magnesium and Alkali Salts: To pass the test.
Acceptance criteria: NMT 1.0%; the weight of the residue is NMT 5 mg.
Mercury: To pass the test.
Acceptance criteria: NMT 0.5 ppm
Loss on Drying: Dry a sample at 200C for 4 h: it loses NMT 2.0% of its weight.
Packaging and Storage: Preserve in well-closed containers.
Calcium Carbonate BP Grade Specifications
CaCO3 --- 100
Action and use: Antacid.
DEFINITION
Content: 98.5 per cent to 100.5 per cent (dried substance).
CHARACTERS
Appearance: White or almost white powder.
Solubility: Practically insoluble in water.
IDENTIFICATION
A. It gives the reaction of carbonates
B. 0.2 ml of solution S (see Tests) gives the reactions of calcium
TESTS
Solution S: Dissolve 5.0 g in 80 ml of dilute acetic acid R . When the effervescence ceases, boil for 2min. Allow to cool, dilute to 100 ml with dilute acetic acid R and filter, if necessary, through a sintered-glass filter.
Substances insoluble in acetic acid: Maximum 0.2 per cent.
Chlorides: Maximum 330 ppm.
Sulphates: Maximum 0.25 per cent.
Arsenic: Maximum 4 ppm, determined on 5 ml of solution S.
Barium: To 10 ml of solution S add 10 ml of calcium sulphate solution R. After at least 15 min, any opalescence in the solution is not more intense than that in a mixture of 10 ml of solution S and 10 ml of distilled water R.
Iron: Maximum 200 ppm.
Magnesium and alkali metals: Maximum 1.5 per cent.
Heavy metals: Maximum 20 ppm.
Calcium Carbonate FCC Food Grade Specifications
CaCO3 Formula weight 100.09
CAS: 471-34-1
DESCRIPTION
Calcium Carbonate occurs as a fine, white or colorless, microcrystalline powder. It is stable in air, and it is practically insoluble in water and in alcohol. The presence of any ammonium salt or carbon dioxide increases its solubility in water, but the presence of any alkali hydroxide reduces the solubility.
Function: pH control agent; nutrient; dough conditioner; firming agent; yeast nutrient.
REQUIREMENTS
Identification: A sample dissolves, with effervescence, in 1 N acetic acid, in 2.7 N hydrochloric acid, and in 1.7 N nitric acid, and the resulting solutions, after boiling, give positive tests for Calcium.
Assay: Not less than 98.0% and not more than 100.5% of CaCO3 after drying.
Acid-Insoluble Substances: Not more than 0.2%.
Arsenic: Not more than 3 mg/kg.
Fluoride: Not more than 0.005%.
Lead: Not more than 3 mg/kg.
Loss on Drying: Not more than 2%.
Magnesium and Alkali Salts: Not more than 1%.
Calcium Carbonate Analytical Reagent Specifications
Calcium Carbonate
CaCO3
Formula Wt 100.09
CAS Number 471-34-1
REQUIREMENTS
Assay (dried basis): 99.0% CaCO3 min
MAXIMUM ALLOWABLE
Insoluble in dilute hydrochloric acid: 0.01%
Ammonium hydroxide precipitate: 0.01%
Chloride (Cl): 0.001%
Sulfate (SO4): 0.0015%
Ammonium (NH4): 0.003%
Barium (Ba): 0.01%
Heavy metals (as Pb): 0.001%
Iron (Fe): 0.003%
Magnesium (Mg): 0.02%
Potassium (K): 0.01%
Sodium (Na): 0.1%
Strontium (Sr): 0.1%
The MSDS-SDS Hazard Statement of Coated Activated Precipitated Calcium Carbonate:
Calcium Carbonate (also Calcite or Limestone) SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 31-Jul-21
1. Product Identification
Product Name & Other Names: Calcium Carbonate; Carbonic acid calcium salt; calcite; aragonite; limestone.
CAS No.: 471-34-1 or 1317-65-3
EINECS EC Number: 207-439-9 or 215-279-6
Molecular Weight: 100.09
Chemical Formula: CaCO3
Relevant uses and uses advised against (if any): Laboratory Chemicals and Industrial Manufacturing Use.
Supplier: As per letterhead.
2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Calcium Carbonate; Carbonic acid calcium salt; calcite; aragonite; limestone.
CAS No.: 471-34-1 or 1317-65-3
EINECS EC Number: 207-439-9 or 215-279-6
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Wash exposed area with soap and water.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
5. Fire Fighting Measures
Fire: Calcium Carbonate is not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: None specified.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Vacuum or sweep up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like acids, fluorine, magnesium with hydrogen.
8. Exposure Controls/Personal Protection
Exposure Limits:
TWA: 15 (mg/m3) from OSHA (PEL) [United States] Inhalation Total.
TWA: 5 (mg/m3) from OSHA (PEL) [United States] Inhalation Respirable.
TWA: 10 (mg/m3) from ACGIH (TLV) [United States]
TWA: 10 (mg/m3) [United Kingdom (UK)] Inhalation Total.
TWA: 4 (mg/m3) [United Kingdom (UK)] Inhalation Respirable.3
Consult local authorities for acceptable exposure limits.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Calcium Carbonate is fine, white powder.
Odor: Odorless.
Odor threshold: Not available.
pH: >7.
Relative density: 2.7 - 2.95
Melting Point: 825C (1517F).
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: 0.001 gm in 100 ml water, soluble in dilute acids.
Viscosity: Not available.
Molecular Weight: 100.09
Chemical Formula: CaCO3
10. Stability and Reactivity
Stability: Calcium Carbonate is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: When heated to decomposition (825C), emits calcium oxide fumes, and liberates carbon dioxide.
Hazardous Polymerization: Will not occur.
Incompatibilities: Acids, fluorine, magnesium with hydrogen.
Conditions to Avoid: Heat, incompatibles.
11. Toxicological Information
Acute toxicity: LD50 Oral - Rat - 6,450 mg/kg(Calcium carbonate)
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Although pure Calcium Carbonate is quite safe in handling, impurities in it can be damaging.
12. Ecological Information
Environmental Fate: No information found.
Environmental Toxicity: No information found.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container of and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMDG/IMO: Not dangerous goods.
Air Transport IATA/ICAO: Not dangerous goods.
15. Regulatory Information
USA Regulations:
SARA 311/312 Hazardous Categorization: Not applicable. See section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.
16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Coated Activated Precipitated Calcium Carbonate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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