Specifications, SDS of Nicotinamide or Niacinamide or Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Nicotinamide or Niacinamide or Vitamin B3 BP Ph Eur USP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number yyy.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Nicotinamide or Niacinamide or Vitamin B3 BP Ph Eur USP FCC Food Grade for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

The Properties, Specifications, Monograph and Uses of Nicotinamide or Niacinamide or Vitamin B3:

Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3 is used as a dietary supplement and medication. It has also been used in many topical agents including sunscreens and cosmetic agents.

DEFINITION
Pyridine-3-carboxamide.
Content: 99.0 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals.
Solubility: Freely soluble in water and in anhydrous ethanol, slightly soluble in methylene chloride.

IDENTIFICATION
First identification: B.
Second identification: A, C
A. Melting point: 128C to 131C.
B. Infrared absorption spectrophotometry.
C. Thin-layer chromatography.

TESTS
Solution S: Dissolve 2.5 g in carbon dioxide-free water and dilute to 50 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than.
pH: 6.0 to 7.5 for solution S.
Related substances: To pass the test.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in vacuo for 18 h.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.

Niacinamide USP Grade Specifications:
C6H6N2O -- 122.12
3-Pyridinecarboxamide;
Nicotinamide CAS 98-92-0
UNII: 25X51I8RD4

DEFINITION
Niacinamide contains NLT 98.5% and NMT 101.5% of niacinamide (C6H6N2O), calculated on the dried basis.

Residue on Ignition: NMT 0.1%
Readily Carbonizable Substances:
Sample solution: Dissolve 200 mg of Niacinamide in 5 mL of sulfuric acid.
Acceptance criteria: The Sample solution has no more color than Matching Fluid A.
Melting Range or Temperature: 128C to 131C
Loss on Drying: Dry a sample over silica gel for 4 h: it loses NMT 0.5% of its weight.

Niacinamide FCC Food Grade Specifications:
Nicotinamide
C6H6N2O Formula weight 122.13
CAS 98-92-0

DESCRIPTION
Niacinamide occurs as a white, crystalline powder. One gram dissolves in about 1 mL of water, in about 1.5 mL of alcohol, and in about 10 mL of glycerin. Its solutions are neutral to litmus.
Function: Nutrient.

REQUIREMENTS
Identification:
A. Transfer about 20 mg of sample into a 1000-mL volumetric flask, dissolve in and dilute to volume with water, mix, and determine the absorbance of the solution in a 1-cm cell at 245 nm and at 262 nm with a suitable pectrophotometer, using water as the blank. The ratio A245/A262 is 0.65 _ 0.02.
B. The infrared absorption spectrum of a potassium bromide dispersion of the sample exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Niacinamide Reference Standard.

Assay: Not less than 98.5% and not more than 101.0% of C6H6N2O after drying.
Lead: Not more than 2 mg/kg.
Loss on Drying: Not more than 0.5%.
Melting Range: Between 128C and 131C.
Readily Carbonizable Substances: Passes test.
Residue on Ignition: Not more than 0.1%.

Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3 SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 12-April-25

Product Name & Other Names: Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3.
CAS No.: 98-92-0
EINECS: EC Number: 202-713-4
Relevant uses and uses advised against (if any): Industrial Manufacturing.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352-IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.

Product Name & Other Names: Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3.
CAS No.: 98-92-0
EINECS: EC Number: 202-713-4

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

Flammability of the Product: Combustible at high temperature.
Auto-Ignition Temperature: 480C literature.
Products of Combustion: Nitrogen oxides, Carbon dioxide, Carbon monoxide, fumes.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Contain spilled material. Avoid touching the spilled material. Do not let the product enter drains. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Do not ingest. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room Temperature.

Airborne Exposure Limits: Not Established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.

Appearance: White crystalline powder.
Odor: Practically odorless.
Odor threshold: Not applicable.
pH: 6.0-7.5 @ 20C 5% for aq. solution.
Relative density: about 1.40 @ 25C.
Boiling Point: Not available.
Melting Point: 128C - 131C.
Flash point: No data found.
Auto-ignition temperature: 480C literature.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Soluble in water.
Viscosity: No data found.

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Oxides of Nitrogen, Carbon dioxide, Carbon monoxide & Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles, heat & light, spark, flame.

Toxicity data
LD50 Oral - Rat - > 2500 mg/kg
LD50 Dermal - Rabbit - > 2,000 mg/kg
Carcinogenic Effects: Not know as carcinogen.
Mutagenic Effects: No data found.
Reproductive Effects: No data found.

Toxicity to fish: static test LC50 - Poecilia reticulata (guppy) - > 1.000 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - > 1.000 mg/l - 24 h.
Persistence and Degradability: Soluble in water Persistence is unlikely based on information available.
Mobility: Will likely be mobile in the environment due to its water solubility.
Bioaccumulation/ Accumulation: Degradable.
Results of PBT and vPvB assessment: No data found for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules..

DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IATA & IMDG/IMO: Not controlled.

USA:
SARA 311/312 Hazards: Acute health hazard. Irritant
California prop. 65: Not listed to cause cancer or birth defects or reproductive harm.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Nicotinamide or Niacinamide or Vitamin B3 Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Nicotinamide or Niacinamide or Vitamin B3 BP Ph Eur USP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number yyy.

Nicotinamide or Niacinamide or Vitamin B3 Manufacturers, Suppliers, Exporters, Wholesalers: