Specifications, SDS of Biotin or Vitamin B7 or Vitamin H Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Biotin or Vitamin B7 or Vitamin H USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number yyy.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Biotin or Vitamin B7 or Vitamin H USP BP Ph Eur FCC Food Grade for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

Biotin or Vitamin B7 or Vitamin H Manufacturer Supplier Exporter

Biotin or Vitamin B7 or Vitamin H or D-Biotin or Bios II or Coenzyme R CAS Number

The Properties, Specifications, Monograph and Uses of Biotin or Vitamin B7 or Vitamin H:

Biotin BP Ph Eur Grade Specifications:
C10H16N2O3S --- 244.3 CAS 58-85-5
Action and use: Vitamin.

DEFINITION
Biotin contains not less than 98.5 per cent and not more than the equivalent of 101.0 per cent of 5-[(3aS,4S,6aR)-2-oxohexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid, calculated with reference to the dried substance.

CHARACTERS
A white or almost white, crystalline powder or colourless crystals, very slightly soluble in water and in alcohol, practically insoluble in acetone. It dissolves in dilute solutions of alkali hydroxides.

IDENTIFICATION
First identification: A
Second identification: B, C
A. Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with biotin CRS.
B. Examine the chromatograms obtained in the test for related substances (see Tests). The principal spot in the chromatogram obtained with test solution (b) is similar in position and size to the principal spot in the chromatogram obtained with reference solution (a).
C. Dissolve about 10 mg in 20 mL of water with heating. Allow it to cool. Add 0.1 mL of bromine water. The bromine water is decolourised.

TESTS
Solution S: Dissolve 0.250 g in a 4 g/L solution of sodium hydroxide and dilute to 25.0 mL with the same alkaline solution.
Appearance of solution: Solution S is clear and colourless.
Specific optical rotation: The specific optical rotation is + 89 to + 93, determined on solution S and calculated with reference to the dried substance.
Related substances: To pass the test.
Loss on drying: Not more than 1.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Not more than 0.1 per cent, determined on 1.0 g.

Biotin USP Grade Specifications:
C10H16N2O3S -- 244.31
1H -Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3aS -(3aα,4β,6aα)]-;
(3aS ,4S ,6aR)-Hexahydro-2-oxo-1H -thieno[3,4-d]imidazole-4-valeric acid CAS 58-85-5
UNII: 6SO6U10H04

DEFINITION
Biotin contains NLT 97.5% and NMT 102.0% of biotin (C10H16N2O3S).

IDENTIFICATION
A. Infrared Absorption.
B. It meets the requirements in Specific Tests for Optical Rotation 〈781S〉, Specific Rotation.
C. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
Related Compounds: To pass the test by chromatography.
Optical Rotation, Specific Rotation: for 20 mg/mL in 0.1 N sodium hydroxide +89° to +93°

Biotin FCC Food Grade Specifications:
cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric
Acid; d-Biotin
C10H16N2O3S Formula weight 244.31
CAS 58-85-5

DESCRIPTION
Biotin occurs as a practically white, crystalline powder. It is stable to air and heat. One-gram dissolves in about 5000 mL of water at 25C and in about 1300 mL of alcohol; it is more soluble in hot water and in dilute alkali, and it is insoluble in other common organic solvents.
Function Nutrient.

Biotin or D-Biotin or Bios II or Coenzyme R or Vitamin B7 or Vitamin H
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 22-Jan-25

Product Name & Other Names: Biotin or D-Biotin or Bios II or Coenzyme R or Vitamin B7 or Vitamin H.
CAS Number: 58-85-5
EINECS EC Number: 200-399-3
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Biotin or D-Biotin or Bios II or Coenzyme R or Vitamin B7 or Vitamin H.
CAS Number: 58-85-5
EINECS EC Number: 200-399-3

Always get medical attention after the first aid is over.
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

Extinguisher Media: Use media suitable to extinguish surrounding fire. Water. Foam. Dry chemical or CO2. Oxides of Carbon, Sulfur, and Nitrogen may arise on decomposition.
Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus. Use water spray to cool unopened containers. Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: 2C to 8°C (Refrigerate).

Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.

Appearance and Odor: White crystalline powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Melting point/freezing point: 229C to 231C.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility in Water: Soluble in water.
Viscosity: No data found.

Stability: Stable under ordinary conditions.
Conditions to Avoid: Heat, humidity, sunlight, strong oxidizing agents.
Incompatibility (Materials to Avoid): Strong oxidizing agents.
Hazardous Decomposition Products: Fumes, Carbon, Sulfur, and Nitrogen oxides.
Hazardous Polymerization: Will not occur.

Toxicity to Animals:
LD50 Oral - Rat - > 2000 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: No data found.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.

Toxicity to fish: No data found.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: Will not accumulate.
Results of PBT and vPvB assessment: No data found for assessment.

Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Follow all the pollution control laws.

DOT USA, TDG Canada & ADR/RID Europe: Not controlled.
IMO/IMDG: Not controlled.
IATA/ICAO: Not controlled.

USA:
SARA 311/312 Hazards: No SARA hazards.
California Prop. 65 Components: Not listed to cause cancer. birth defects or reproductive harm.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Biotin or Vitamin B7 or Vitamin H or D-Biotin or Bios II or Coenzyme R Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Biotin or Vitamin B7 or Vitamin H USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number yyy.

Biotin or Vitamin B7 or Vitamin H or D-Biotin or Bios II or Coenzyme R Manufacturers, Suppliers, Exporters, Wholesalers: