Specifications, Uses, SDS of Edetic Acid EDTA Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Edetic Acid EDTA USP NF BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 60-00-4.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Edetic Acid EDTA for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

CAS Number 60-00-4, EINECS EC Number 200-449-4, HS code 292121** or 29224990 or 29212100, Molecular Weight 292.2, Chemical Formula C10H16N2O8

Edetic Acid or EDTA is the acid form of edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties. Edetic acid binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys. This results in a decrease in serum calcium levels. This agent is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning. This white, water-soluble solid is widely used to bind to iron and calcium ions. In industry, EDTA is mainly used to sequester metal ions in aqueous solution. In the textile industry, it prevents metal ion impurities from modifying colours of dyed products. EDTA is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions. It is also used in soft drinks. In shampoos, cleaners, and other personal care products, EDTA salts are used as a sequestering agent to improve their stability in air.

Edetic Acid USP NF Grade Specifications:
C10H16N2O8 --- 292.24
Glycine, N,N-1,2-ethanediylbis[N-(carboxymethyl)-;
(Ethylenedinitrilo)tetraacetic acid CAS 60-00-4

DEFINITION
Edetic Acid contains NLT 98.0% and NMT 100.5% of edetic acid (C10H16N2O8).

ASSAY
Procedure
Standard: 200 mg of chelometric standard calcium carbonate, previously dried to 110C; for 2 h and cooled in a desiccator
Sample solution: Transfer 1.4 g of Edetic Acid to a 100-mL volumetric flask, dissolve in 11 mL of 1 N sodium hydroxide, dilute with water to volume, with cooling if necessary, and mix.
Analysis: Add 10 mL of water to the Standard, swirl to form a slurry, and cover the beaker with a watch glass. Without removing the watch glass, add 2 mL of 3 N hydrochloric acid from a pipet, and swirl to dissolve. Wash down the sides of the container, the outer surface of the pipet, and the watch glass with water, and dilute with water to 100 mL. While stirring with a magnetic stirrer, add 30 mL of the Sample solution from a 50-mL buret. Add 10 mL of 1 N sodium hydroxide and 300 mg of hydroxy naphthol blue and continue the titration with the Sample solution to a blue endpoint.
Calculate the percentage of edetic acid (C10H16N2O8) in the portion of sample taken:
Result = [W/(V x C)] x (Mr1/Mr2) x 100
W = weight of calcium carbonate (mg)
V = volume of the Sample solution consumed in the titration (mL)
C = concentration of the Sample solution (mg/mL)
Mr1 = molecular weight of edetic acid, 292.24
Mr2 = molecular weight of calcium carbonate, 100.09
Acceptance criteria: 98.0% to 100.5%

Specifications of Disodium Edetate BP Ph Eur
C10H14N2Na2O8,2H2O -- 372.2 -- CAS 139-33-3

DEFINITION
Disodium dihydrogen (ethylenedinitrilo)tetraacetate dihydrate.
Content: 98.5 per cent to 101.0 per cent.

CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Soluble in water, practically insoluble in ethanol (96 per cent).

IDENTIFICATION
First identification A, B, D.
Second identification B, C, D.
A. Infrared absorption spectrophotometry.
B. Dissolve 2 g in 25 ml of water, add 6 ml of lead nitrate solution, shake and add 3 ml of potassium iodide solution. No yellow precipitate is formed. Make alkaline to red litmus paper by the addition of dilute ammonia. Add 3 ml of ammonium oxalate solution R. No precipitate is formed.
C. Dissolve 0.5 g in 10 ml of water and add 0.5 ml of calcium chloride solution. Make alkaline to red litmus paper by the addition of dilute ammonia and add 3 ml of ammonium oxalate solution. No precipitate is formed.
D. It gives the reactions of sodium.

TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 4.0 to 5.5 for solution S.
Impurity A: Liquid chromatography. Carry out the test protected from light.
To pass the test
Limit: impurity A: not more than the area of the corresponding peak in the chromatogram obtained with the reference solution (0.1 per cent).
Iron: Maximum 80 ppm.
Heavy metals: Maximum 20 ppm

Specifications of Disodium EDTA FCC Food Grade
Disodium Ethylenediaminetetraacetate; Disodium (Ethylenedinitrilo)tetraacetate; Disodium Edetate
C10H14N2Na2O8-2H2O Formula wt 372.24
INS: 386 CAS: [CAS 6381-92-6]

DESCRIPTION
EDTA Disodium occurs as a white, crystalline powder. It is soluble in water.

REQUIREMENTS
Identification
A. A 1:20 aqueous solution responds to the flame test for Sodium.
B. Add 2 drops of ammonium thiocyanate TS and 2 drops of ferric chloride TS to 5 mL of water in a test tube. Add about 50 mg of sample to the deep red solution so obtained, and mix. The deep red color disappears.
C. The infrared absorption spectrum of a potassium bromide dispersion of sample exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Edetate Disodium Reference Standard.

Assay: Not less than 99.0% and not more than 101.0% of C10H14N2Na2O8-2H2O.
Calcium: Negative.
Lead: Not more than 10 mg/kg.
Nitrilotriacetic Acid: Not more than 0.1%.
pH of a 1:100 Solution: Between 4.3 and 4.7.

EDTA or Edetic Acid SDS, Safety Data Sheet
Ethylenediaminetetraacetic acid MSDS, Material Safety Data Sheet 21-Aug-21

Product Name & Other Names: EDTA or Edetic acid or Versene acid or Ethylenediaminetetraacetic acid.
CAS Number: 60-00-4
EINECS EC Number: 200-449-4
Molecular Weight: 292.24
Chemical Formula: (HOCOCH2)2NCH2CH2N- (HOCOCH2)2
Relevant uses and uses advised against (if any): For Industrial use only.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, oral Category 5, H303
Serious eye damage/eye irritation Category 1, H319
Hazardous to the aquatic environment, acute hazard Category 3 H402

Hazard statements:
H303: May be harmful if swallowed
H319: Causes serious eye irritation.
H402: Harmful to aquatic life.

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P330: Rinse mouth.
P270: Do not eat, drink, or smoke when using this product.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+P352-IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to comply with local, state, and federal regulations.

Product Name & Other Names: EDTA or Edetic acid or Versene acid or Ethylenediaminetetraacetic acid.
CAS Number: 60-00-4
EINECS EC Number: 200-449-4

Inhalation: Remove to fresh air. If breathing is difficult, give oxygen. Get Medical advice.
Ingestion: Give several glasses of water to drink to dilute the effect and get medical advice.
Skin Contact: Remove any contaminated clothing and shoes. Wash soap or mild detergent and water for at least 15 minutes. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention.

Fire: Not considered to be a fire hazard. However, it can burn at high temperatures.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong bases, aluminum, copper, copper alloys, nickel.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g., lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice.

Appearance: EDTA is white crystals.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: around 0.9
Melting Point: 250C (483F).
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: 0.05 g/100 ml @ 20C (68F)
Viscosity: Not available.
Molecular Weight: 292.24
Chemical Formula: (HOCOCH2)2NCH2CH2N- (HOCOCH2)2

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents, strong bases, aluminum, copper, copper alloys, nickel.
Conditions to Avoid: Incompatibles, heat, and sunlight.

Oral LD50 Rat: >2000 mg/kg.
Dermal LD50 Rabbit: >5000 mg/kg
Carcinogenicity: Not reported human as a carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Environmental Fate: When released into the soil, it is expected to leach into groundwater. When released into the soil, this material may biodegrade to a moderate extent. When released into the soil, this material is not expected to evaporate significantly. When released into water, this material is not expected to evaporate significantly. This material is not expected to significantly bio accumulate. When released into the air, this material is expected to be readily degraded.
Environmental Toxicity:
24 Hr. LC50 rainbow trout: 340 mg/L;
96 Hr. LC50 bluegill sunfish:486 mg/L;
96 Hr. LC50 channel catfish: 129 mg/L.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with legal requirements.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
Sea Transport IMDG/IMO: Not Regulated.
Air Transport IATA/ICAO: Not Regulated.

SARA 311/312 Hazards: Acute Health Hazard. See section 2.
California Prop 65: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Edetic Acid EDTA Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Edetic Acid EDTA USP NF BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 60-00-4.

Edetic Acid EDTA Manufacturers, Suppliers, Exporters, Wholesalers: