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Specifications, Properties, Uses, SDS of Calcium Ascorbate USP BP Ph Eur FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 5743-27-1 or 5743-28-2. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Calcium Ascorbate or Vitamin C Calcium salt for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Calcium Ascorbate or Vitamin C Calcium salt CAS Number 5743-27-1 or 5743-28-2
For Properties Specifications Uses of Calcium Ascorbate or Vitamin C Calcium salt Click Properties, Specifications, Uses, Price, Process of Calcium Ascorbate or Vitamin C Calcium salt Manufacturer.
For For SDS MSDS Sheet of Calcium Ascorbate or Vitamin C Calcium salt Click SDS Safety Data Sheet MSDS Sheet of Calcium Ascorbate or Vitamin C Calcium salt Manufacturer.
The Properties, Specifications, Monograph and Uses of Calcium Ascorbate or Vitamin C Calcium salt:
CAS Number: 5743-27-1 or 5743-28-2, EINECS EC Number: 227-261-5, Molecular Formula: Ca(C6H7O6)2-2H2O, Molecular Weight: 426.34, HS Code 29362990 or 29333990 or 38220090
Calcium ascorbate is an organic calcium salt resulting from the replacement of the proton from the hydroxy group of ascorbic acid by a calcium ion. Calcium ascorbate used as a chemical preservative is generally recognized as safe when used in accordance with good manufacturing or feeding practice. As a food additive, it has the E number E 302. It is approved for use as a food in several countries. It is used as an antioxidant. Calcium ascorbate can extend the shelf life of food and beverage products and protect against deterioration of color, flavor, and overall quality.
Calcium Ascorbate USP Grade Specifications:
C12H14CaO12-2H2O --- 426.34
DEFINITION
Calcium Ascorbate contains NLT 98.0% and NMT 101.0% of calcium ascorbate dihydrate (C12H14CaO12-2H2O), calculated on the as-is basis.
IDENTIFICATION
A. Identification Tests - General, Calcium: A 100 mg/mL solution meets the requirements.
B. A 100 mg/mL solution decolorizes a 100 mg/mL solution of dichlorophenol–indophenol.
C. Infrared Absorption.
ASSAY
Procedure
Sample: 300 mg of Calcium Ascorbate
Blank: 50 mL of water
Titrimetric system
Mode: Direct titration
Titrant: 0.1 N iodine
Endpoint detection: Visual
Analysis: Transfer the Sample into a 250-mL conical flask, add 50 mL of water, and mix to dissolve. Immediately titrate with the Titrant, adding 3 mL of starch TS as the endpoint is approached. Perform a Blank determination.
Calculate the percentage of calcium ascorbate dihydrate (C12H14CaO12-2H2O) in the Sample taken:
Result = {[( V S − V B ) × N × F]/W} × 100
V S = Titrant volume consumed by the Sample (mL)
V B = Titrant volume consumed by the Blank (mL)
N = Titrant normality (mEq/mL)
F = equivalency factor, 106.6 mg/mEq
W = Sample weight (mg)
Acceptance criteria: 98.0%–101.0% on the as-is basis
Limit of Fluoride: To pass the test. --- NMT 10 ppm
Optical Rotation, Specific Rotation:
Sample solution: 50 mg/mL in carbon dioxide-free water [Note— Perform measurements immediately after preparation.]
Acceptance criteria: +95° to +97°
pH:
Sample solution: 100 mg/mL
Acceptance criteria: 6.8–7.4
Loss on Drying: Dry 3 g at 105C for 2 h: it loses NMT 0.1% of its weight.
Packaging and Storage: Preserve in tight, light-resistant containers.
Calcium Ascorbate BP Ph Eur Grade Specifications:
C12H14CaO12-2H2O --- 426.3 --- CAS 5743-28-2
Action and use: Excipient.
DEFINITION
Calcium di[(R)-2-[(S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate] dihydrate.
Content: 99.0 per cent to 100.5 per cent of C12H14CaO12,2H2O.
CHARACTERS
Appearance: White or slightly yellowish, crystalline powder.
Solubility: Freely soluble in water, practically insoluble in ethanol (96 per cent).
IDENTIFICATION
First identification: A, B, E
Second identification: A, C, D, E
A. Specific optical rotation (see Tests).
B. Infrared absorption spectrophotometry.
C. Dilute 1 mL of solution S (see Tests) to 10 mL with water. To 2 mL of the solution add 0.2 mL of a 100 ;g/L solution of ferrous sulfate. A deep violet colour develops.
D. To 1 mL of solution S add 0.2 mL of dilute nitric acid and 0.2 mL of silver nitrate solution. A grey precipitate is formed.
E. The substance gives reaction (b) of calcium.
TESTS
Solution S: Dissolve 5.00 g in carbon dioxide-free water and dilute to 50.0 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution. Examine the colour of the solution immediately after preparation of the solution.
pH: 6.8 to 7.4 for solution S.
Specific optical rotation: + 95 to + 97 (dried substance), determined using freshly prepared solution S.
Fluorides: Maximum 10 ppm.
Copper: Maximum 5 ppm.
Iron: Maximum 2 ppm.
Loss on drying: Maximum 0.1 per cent, determined on 1.000 g by drying in an oven at 105C for 2 h.
Specifications of Calcium Ascorbate FCC Food Grade:
C12H14CaO12-2H2O Formula wt 426.34
INS: 302 CAS: 5743-27-1
DESCRIPTION
Calcium Ascorbate occurs as a white to slightly yellow, crystalline powder. It is soluble in water, slightly soluble in alcohol, and insoluble in ether. The pH of a 1:10 aqueous solution is between 6.8 and 7.4.
Function: Antioxidant.
REQUIREMENTS
Identification: A 1:10 aqueous solution gives positive tests for Calcium, Appendix IIIA, and it decolorizes dichlorophenol–indophenol.
Assay: Not less than 98.0% and not more than 100.5% of C12H14CaO12-2H2O.
Lead: Not more than 2 mg/kg.
Optical (Specific) Rotation: Between +95° and +97°.
Oxalate: Passes test.
The MSDS-SDS Hazard Statement of Calcium Ascorbate or Vitamin C Calcium salt:
Calcium ascorbate or Ascorbic acid calcium salt or Vitamin C calcium salt SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 22-Jul-21
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Calcium ascorbate or Ascorbic acid calcium salt or Calcium diascorbate or Vitamin C Calcium salt.
CAS Number: 5743-27-1 or 5743-28-2
EINECS EC Code: 227-261-5
Chemical Formula: Ca(C6H7O6)2-2H2O
Molecular Weight: 426.34
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Calcium ascorbate or Ascorbic acid calcium salt or Calcium diascorbate or Vitamin C Calcium salt.
CAS Number: 5743-27-1 or 5743-28-2
EINECS EC Code: 227-261-5
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Notes to Physician: Treat symptomatically.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: Calcium oxide, Fumes and Oxides of carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: White crystalline powder.
Odor: Odorless.
Odor threshold: Not available.
pH: about 6 to 7.5
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Chemical Formula: Ca(C6H7O6)2-2H2O
Molecular Weight: 426.34
Section 10: Stability and Reactivity Data
Stability: It is stable.
Conditions of instability: Incompatible materials
Incompatibility with various substances: Heat, light, strong oxidizing agents.
Polymerization: Will not occur.
Hazardous decomposition products formed under fire conditions: Carbon oxides, Calcium oxide, Fumes.
Section 11: Toxicological Information
Toxicity to Animals: Not available.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Reproductive Toxicity: No information available.
Developmental Effects: No information available.
Teratogenicity: No information available.
Section 12: Ecological Information
Ecotoxicity: The product is not considered harmful to aquatic organisms or to cause long-term adverse effects in the environment. Not dangerous for the ozone layer.
Products of Biodegradation: The product itself and its products of degradation are not toxic.
Persistence and Degradability: No information available.
Bioaccumulation/ Accumulation: No information available.
Mobility: No information available.
Results of PBT and vPvB assessment: No information available.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
Sea Transport IMDG/IMO: Not dangerous goods
Air Transport IATA/ICAO: Not dangerous goods.
Section 15: Other Regulatory Information
USA Federal and State Regulations:
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Calcium Ascorbate or Vitamin C Calcium salt Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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