Specifications, Uses, SDS of Potassium Gluconate Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Potassium D-gluconate or Potassium Gluconate USP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 299-27-4 or (35398-15-3 for monohydrate).
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Potassium D-gluconate or Potassium Gluconate for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

Potassium Gluconate Manufacturer Supplier Exporter

Potassium Gluconate or Potassium D-gluconate CAS Number 299-27-4 or (35398-15-3 for monohydrate)

The Properties, Specifications, Monograph and Uses of Potassium Gluconate or Potassium D-gluconate:

CAS Number 299-27-4 or (35398-15-3 for monohydrate), EINECS EC Number 206-074-2, HS Code 29181690 or 38220090; Molecular Weight 234.25, Molecular Formula: C6H11KO7

Potassium gluconate or Potassium D-gluconate is the potassium salt of the conjugate base of gluconic acid. A normal level of potassium in the blood is important. Potassium gluconate is used as a mineral supplement and sequestrant. It is sold over-the-counter as tablets or capsules providing up to 593 mg of potassium gluconate, thereby containing 99 mg or 2.53 milliequivalents of elemental potassium. As a food additive, potassium gluconate is used as an acidity regulator and yeast food. It is known as E number reference E577.

Specifications of Potassium Gluconate FCC Food Grade
D-Gluconic Acid, Monopotassium Salt; Monopotassium DGluconate
C6H11KO7 -- Formula wt, anhydrous 234.25
C6H11KO7-H2O -- Formula wt, monohydrate 252.26
CAS: anhydrous CAS 299-27-4
CAS: monohydrate CAS 35398-15-3

DESCRIPTION
Potassium Gluconate occurs as a white or yellow-white, crystalline powder or granules. It is anhydrous or the monohydrate. It is freely soluble in water and in glycerin, slightly soluble in alcohol, and insoluble in ether.

Identification:
A. A sample responds to the flame test for Potassium.
B. Dissolve a quantity of sample in water, heating in a water bath at 60C if necessary, to obtain a Test Solution containing 10 mg/mL. Similarly, prepare a Standard Solution of USP Potassium Gluconate Reference Standard in water, diluting to 10 mg/mL. To prepare a Spray Reagent, dissolve 2.5 g of ammonium molybdate in about 50 mL of 2 N sulfuric acid in a 100-mL volumetric flask, add 1.0 g of ceric sulfate, swirl to dissolve, dilute with 2 N sulfuric acid to volume, and mix. Apply separate 5-L portions of the Test Solution and the Standard Solution on a suitable thin-layer chromatographic plate, coated with a 0.25-mm layer of chromatographic silica gel, and allow to dry. Develop the chromatogram in a solvent system consisting of a 50:30:10:10 mixture of alcohol, water, ammonium hydroxide, and ethyl acetate until the solvent front has moved about three-fourths of the length of the plate. Remove the plate from the chamber, and dry at 110C for 20 min. Allow to cool, and spray with Spray Reagent. After spraying, heat the plate at 110C for about 10 min. The principal spot obtained from the Test Solution corresponds in color, size, and Rf value to that obtained from the Standard Solution.
C. The infrared absorption spectrum of a mineral oil dispersion of the sample, previously dried, exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Potassium Gluconate Reference Standard.
Assay: Not less than 98.0% of C6H11KO7, calculated on the dried basis.
Lead: Not more than 2 mg/kg.
Loss on Drying: Anhydrous: Not more than 3.0%; Monohydrate: Between 6.0% and 7.5%.
Reducing Substances: Not more than 1.0%.

Specifications of Potassium Gluconate USP Grade
C6H11KO7(anhydrous) -- 234.25
d-Gluconic acid, monopotassium salt.
Monopotassium d-gluconate -- CAS 299-27-4.
Monohydrate 252.26 -- CAS 35398-15-3.

Potassium Gluconate is anhydrous or contains one molecule of water of hydration. It contains not less than 97.0 percent and not more than 103.0 percent of C6H11KO7, calculated on the dried basis.

Identification:
A: Infrared Absorption.
B: It responds to the flame test for Potassium.
C: It responds to Identification test B for Gluconate under Calcium Gluconate.
Loss on drying: Dry it in vacuum at 105C for 4 hours: the anhydrous form loses not more than 3.0% of its weight, and the monohydrate loses between 6.0% and 7.5% of its weight.
Heavy metals: Dissolve 1 g in 10 mL of water, add 6 mL of 3 N hydrochloric acid, and dilute with water to 25 mL: the limit is 0.002%.
Reducing substances: Transfer 1.0 g to a 250-mL conical flask, dissolve in 10 mL of water, and add 25 mL of alkaline cupric citrate TS. Cover the flask, boil gently for 5 minutes, accurately timed, and cool rapidly to room temperature. Add 25 mL of 0.6 N acetic acid, 10.0 mL of 0.1 N iodine VS, and 10 mL of 3 N hydrochloric acid, and titrate with 0.1 N sodium thiosulfate VS, adding 3 mL of starch TS as the endpoint is approached. Perform a blank determination, omitting the specimen, and note the difference in volumes required. Each mL of the difference in volume of 0.1 N sodium thiosulfate consumed is equivalent to 2.7 mg of reducing substances (as dextrose): the limit is 1.0%.
Assay:
Potassium stock solution: Dissolve 190.7 mg of potassium chloride, previously dried at 105C for 2 hours, in water. Transfer to a 1000-mL volumetric flask, dilute with water to volume, and mix. Transfer 100.0 mL of this solution to a 1000-mL volumetric flask, dilute with water to volume, and mix. This solution contains 10 µg of potassium (equivalent to 19.07 µg of potassium chloride) per mL.
Standard preparations— To separate 100-mL volumetric flasks transfer 10.0, 15.0, and 20.0 mL, respectively, of Potassium stock solution. To each flask add 2.0 mL of sodium chloride solution (1 in 5) and 1.0 mL of hydrochloric acid, dilute with water to volume, and mix. The Standard preparations contain, respectively, 1.0, 1.5, and 2.0 µg of potassium per mL.
Assay preparation— Transfer about 180 mg of Potassium Gluconate, accurately weighed, to a 1000-mL volumetric flask, add water to volume, and mix. Filter a portion of the solution. Transfer 5.0 mL of the filtrate to a 100-mL volumetric flask, add 2.0 mL of sodium chloride solution (1 in 5) and 1.0 mL of hydrochloric acid, dilute with water to volume, and mix.
Procedure: Concomitantly determine the absorbances of the Standard preparations and the Assay preparation at the potassium emission line of 766.5 nm, with a suitable atomic absorption spectrophotometer equipped with a potassium hollow-cathode lamp and an air–acetylene flame, using water as the blank. Plot the absorbance of the Standard preparation versus concentration, in µg per mL, of potassium, and draw the straight line best fitting the three plotted points. From the graph so obtained, determine the concentration, in µg per mL, of potassium in the Assay preparation. Calculate the weight, in mg, of C6H11KO7 in the Potassium Gluconate taken by the formula:

in which C is the concentration, in µg per mL, of potassium in the Assay preparation, 234.25 is the molecular weight of potassium gluconate, and 39.10 is the atomic weight of potassium.

The MSDS-SDS Hazard Statement of Potassium Gluconate or Potassium D-gluconate:

Potassium Gluconate SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 03-Jul-21

Product Name & Other Names: Potassium gluconate or D-Gluconic acid monopotassium salt or Monopotassium gluconate or Potassium D-gluconate.
CAS#: 299-27-4
EINECS EC Number: 206-074-2
Chemical Formula: C6H11KO7 on anhydrous basis
Molecular Weight: 234.25 on anhydrous basis
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Product Name & Other Names: Potassium gluconate or D-Gluconic acid monopotassium salt or Monopotassium gluconate or Potassium D-gluconate.
CAS#: 299-27-4
EINECS EC Number: 206-074-2

Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If Potassium Gluconate is inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do Not induce vomiting unless directed to do so by medical personnel. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing.
Notes to Physician: Provide general supportive measures and treat symptomatically.

Flammability of the Product: Not classed as fire hazard but it may be combustible at high temperature.
Flash Points: Not available.
Flammable Limits: Not available.
Products of Combustion: Oxides of Potassium and carbon along with fumes .
Explosion Hazards in Presence of Various Substances: Not available.
Fire Fighting Media and Instructions: Use DRY chemical powder, water spray, carbon dioxide, fog, or foam. Do not use water jet. Cool containers exposed to flames with water until well after the fire is out.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Engineering Controls: No exposure standards allocated. Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Solid. (Off-White Powder)
Odor: Odorless.
Odor threshold: Not available.
Color: Not available.
pH (1% soln/water): 7-10.
Relative density: Not available.
Boiling Point: Decomposes.
Melting Point: Decomposes.
Critical Temperature: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in cold water, hot water. Freely soluble in glycerin; practically insoluble in dehydrated alcohol, in ether, in benzene, and in chloroform.
Viscosity: Not available.
Molecular Weight: 234.25
Molecular Formula: C6H11KO7

Stability: Stable.
Incompatibility with various substances: Oxidizing agents
Hazardous Decomposition Products: May form carbon dioxide and carbon monoxide, various hydrocarbons fumes and oxide of Potassium.
Corrosivity: Not available.
Polymerization: Will not occur.

Toxicity to Animals:
LD50 Oral: 9100 mg/kg Mouse
LD50 Oral: 6060 mg/kg Rat
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
Sea Transport IMDG/IMO: Not regulated.
Air Transport IATA/ICAO: Not regulated.

USA:
SARA 311/312 Hazards: No SARA Hazards.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Potassium Gluconate or Potassium D-gluconate Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Potassium D-gluconate or Potassium Gluconate USP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 299-27-4 or (35398-15-3 for monohydrate).

Potassium Gluconate or Potassium D-gluconate Manufacturers, Suppliers, Exporters, Wholesalers: