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King of Chemicals Manufacturers Vecuronium Bromide and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of Vecuronium Bromide API BP Ph Eur EP USP IP Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 50700-72-6. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Vecuronium Bromide for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Vecuronium Bromide CAS Number 50700-72-6
For Properties Specifications Uses of Vecuronium Bromide Click Properties, Specifications, Uses, Price, Process of Vecuronium Bromide Manufacturer.
For For SDS MSDS Sheet of Vecuronium Bromide Click SDS Safety Data Sheet MSDS Sheet of Vecuronium Bromide Manufacturer.
The Properties, Specifications, Monograph and Uses of Vecuronium Bromide:
Vecuronium bromide is an intermediate-acting, non-depolarizing neuromuscular blocking agent used primarily to induce temporary skeletal muscle relaxation and paralysis. It is a critical adjunct medication in anesthesiology and critical care settings. It is used in Facilitating Endotracheal Intubation, Surgical Muscle Relaxation, Assisting Mechanical Ventilation, etc.
Vecuronium Bromide BP Ph Eur Grade Specifications:
C34H57BrN2O4 --- 638 CAS 50700-72-6
Action and use: Non-depolarizing neuromuscular blocker.
DEFINITION
1-[3α,17β-Bis(acetyloxy)-2β-(piperidin-1-yl)-5α-androstan-16β-yl]-1-methylpiperidin-1-ium bromide.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or almost white crystals or crystalline powder.
Solubility: Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol.
IDENTIFICATION
A. Specific optical rotation (see Tests).
B. Infrared absorption spectrophotometry.
C. It gives reaction (a) of bromides.
TESTS
Solution S: Dissolve 0.500 g in a 5.15 g/L solution of hydrochloric acid and dilute to 50.0 mL with the same solution.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Specific optical rotation: + 30.5 to + 35.0 (anhydrous substance), determined on solution S.
Impurity B: To pass the test by Thin-layer chromatography.
Related substances: To pass the test by Liquid chromatography.
Water: Maximum 4.0 per cent, determined on 0.300 g.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Storage: In an airtight container, protected from light and moisture.
Vecuronium Bromide USP Grade Specifications:
C34H57BrN2O4 --- 637.73
Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl) androstan-16-yl]-1-methyl-, bromide;
1-(3α,17β-Dihydroxy-2β-piperidino-5α-androstan-16β,5α-yl)-1-methylpiperidinium bromide, diacetate
CAS 50700-72-6
UNII: 7E4PHP5N1D
UNII: 5438723848
DEFINITION
Vecuronium Bromide contains NLT 98.0% and NMT 102.0% of C34H57BrN2O4, calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption: Meets the requirements
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
Organic Impurities: To pass the test by chromatography.
Optical Rotation, Specific Rotation: Sample solution: 10 mg/mL, in dehydrated alcohol. Acceptance criteria: −16° to −20° at 20C.
Bacterial Endotoxins: NMT 10 USP Endotoxin Units/mg of vecuronium bromide.
Loss on Drying: ;Dry a sample at 105° for 2 h: it loses NMT 2.5% of its weight.
Packaging and Storage: Preserve in tight containers, and store at room temperature.
Vecuronium Bromide EP IP Grade is also supplied.
The MSDS-SDS Hazard Statement of Vecuronium Bromide:
Vecuronium Bromide SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: Vecuronium Bromide.
CAS No.: 50700-72-6
EINECS EC Number: 256-723-9
Molecular Weight: 637.74
Chemical Formula: C34H57BrN2O4
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.
2.Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements Irritant Harmful |
Signal Words: Warning
Hazard statements:
H302 Harmful if swallowed.
Precautionary statements:
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P314 Get Medical advice/attention if you feel unwell.
P301+P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P360 Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P501 Dispose of contents/ container to an approved waste disposal plant.
3. Composition/Information on Ingredients
Product Name & Other Names: Vecuronium Bromide.
CAS No.: 50700-72-6
EINECS EC Number: 256-723-9
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reusing. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Fire: Not considered to be a fire hazard.
Hazardous Decomposition Products: Decomposition forms hydrogen bromide, nitrogen oxides and ammonia.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Water spray may be used to keep fire exposed containers cool. Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove it into an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: In an airtight container, protected from light and moisture. Heat Sensitive. Short term storage at room temperature is ok. Frozen storage is preferred.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded and engineering controls are not feasible, a half face piece particulate respirator (NIOSH type N95 or better filters) may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece particulate respirator (NIOSH type N100 filters) may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White or almost white crystals or crystalline powder.
Odor: No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Boiling Point: No data found.
Melting Point: 227C to 229C literature. 235C is also cited.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor Density (Air=1): No data found.
Vapor Pressure (mm Hg): No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility(ies): Slightly soluble in water, freely soluble in methylene chloride.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: Decomposition forms hydrogen bromide, nitrogen oxides and ammonia.
Hazardous Polymerization: Will not occur.
Incompatibilities: Concentrated acids, strong bases, oxidizing agents.
Conditions to Avoid: Heat, moisture, incompatibles.
11. Toxicological Information
Toxicity : LD50 Oral - Rat - 455 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.
12. Ecological Information
Toxicity to fish: No data found.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility. Dispose of containers and unused material in accordance with legal requirements. Follow all the pollution control laws.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
IMDG/IMO & IATA/ICAO: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312: See section 2.
California No Significant Risk Level: Not listed.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Vecuronium Bromide Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- October 30, 2026
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If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
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