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King of Chemicals Manufacturers Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate API BP Ph Eur EP USP NF Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 53956-04-0. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate BP Ph Eur EP USP NF Grade for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate CAS Number 53956-04-0
For Properties Specifications Uses of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate Click Properties, Specifications, Uses, Price, Process of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate Manufacturer.
For For SDS MSDS Sheet of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate Click SDS Safety Data Sheet MSDS Sheet of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate Manufacturer.
The Properties, Specifications, Monograph and Uses of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate:
Ammonium Glycyrrhizinate BP Ph Eur Grade Specifications:
C42H65NO16 --- 840 CAS 53956-04-0
DEFINITION
Mixture of ammonium 18α- and 18β-glycyrrhizate (ammonium salt of (20β)-3β-[[2-O-(β-D-glucopyranosyluronic acid)-α-D-glucopyranosyluronic acid]oxy]-11-oxoolean-12-en-29-oic acid), the 18β-isomer being the main component.
Content: 98.0 per cent to 102.0 per cent (anhydrous substance).
CHARACTERS
Appearance: White or yellowish-white, hygroscopic powder.
Solubility: Slightly soluble in water, very slightly soluble in anhydrous ethanol, practically insoluble in acetone. It dissolves in dilute solutions of acids and of alkali hydroxides.
IDENTIFICATION
A. Infrared absorption spectrophotometry
B. Dissolve 0.1 g in 20 mL of water, add 2 mL of dilute sodium hydroxide solution R and heat cautiously. On heating, the solution gives off vapours that may be identified by the alkaline reaction of wet litmus paper.
Appearance of solution: The solution is clear and not more intensely coloured than reference solution.
Dissolve 1.0 g in ethanol (20 per cent V/V) and dilute to 100.0 mL with the same solvent.
Specific optical rotation: + 49.0 to + 54.0 (anhydrous substance).
Dissolve 0.5 g in ethanol (50 per cent V/V) and dilute to 50.0 mL with the same solvent.
Related substances: To pass the test by Liquid chromatography.
Water: Maximum 6.0 per cent, determined on 0.250 g.
Sulfated ash: Maximum 0.2 per cent, determined on 1.0 g.
Storage: In an airtight container.
Ammonium Glycyrrhizate USP NF Specifications:
C42H62O16-NH3 --- 840.08
Monoammonium glycyrrhizinate;
Glycyrrhizic acid ammonium salt;
α-d-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-d-glucopyranuronosyl-, ammonium salt (1:1);
α-d-Glucopyranosiduronic acid, (3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-d-glucopyranuronosyl-, monoammonium salt CAS 53956-04-0
UNII: 3VRD35U26C
UNII: 6FO62043WK
DEFINITION
Ammonium Glycyrrhizate is a mixture of ammonium 18α- and 18β-glycyrrhizate (ammonium salt of (20β)-3β-[[2-O-(β-d-glucopyranosyluronic acid)-α-d-glucopyranosyluronic acid]oxy]-11-oxoolean-12-en-29-oic acid), and the 18β-isomer is the main component. It contains NLT 78.0% and NMT 102.0% of ammonium 18α- and 18β-glycyrrhizate, on the anhydrous basis.
IDENTIFICATION
A. The retention times of the peaks of 18α- and 18β-glycyrrhizic acid from the Sample solution correspond to those from the System suitability solution, as obtained in the Content of Ammonium 18α- and 18β-Glycyrrhizate. [Note— The peak of 18α-glycyrrhizic acid could be absent in the Sample solution.]
B. Identification Tests—General, Ammonium.
Residue on Ignition:
Sample: 1.0 g
Acceptance criteria: NMT 0.5%
Limit of Organic Impurities: To pass the test by chromatography.
Optical Rotation, Specific Rotation:
Sample solution: 10.0 mg/mL of Ammonium Glycyrrhizate in 50% ethanol
Acceptance criteria: +49.0 to +55.0 on the anhydrous basis
Water Determination: Acceptance criteria: NMT 6.0%
Packaging and Storage: Preserve in tight containers, and store in a cool, dry place.
Ammonium Glycyrrhizinate EP Grade is also manufactured as per monograph.
The MSDS-SDS Hazard Statement of Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate:
Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate SDS MSDS Sheet
Material Safety Data Sheet
1 - Product Identification
Product Name & Other Names: Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate.
CAS Number 53956-04-0
EINECS EC Number: 258-887-7
Molecular Formula: C42H61O16-NH4
Molecular Weight: 839.96
Relevant uses and uses advised against (if any): Laboratory and Industrial Manufacturing.
SUPPLIER: As per letterhead.
2 - Hazards identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Eye irritation (Category 2A), H319
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements Irritant |
Signal Words: Warning
Hazard statements:
H319: Causes serious eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink, or smoke when using this product.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
3 - Composition / information on ingredients
Product Name & Other Names: Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate or Monoammonium Glycyrrhizinate.
CAS Number 53956-04-0
EINECS EC Number: 258-887-7
4 - First aid measures
Always seek medical attention after first aid measures are provided.
Eye contact: Immediately flush eyes with plenty of clean waterfor an extended time, not less than five (5) minutes. Flush longer if there is any indication of residual chemical in the eye. Ensure adequate flushing of the eyes by separating the eyelids with fingers androll eyes in a circular motion.
Skin contact: Immediately remove contaminated clothing and shoes. Wash the affected area with plenty of soap and water until no evidence of the chemical remains. Launder clothing before reuse. If irritation develops, call a physician.
Inhalation: If affected, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration.
Ingestion: Do not induce vomiting. Rinse out the mouth with water. Never give anything by mouth to an unconscious person. Get medical attention immediately.
5 - Firefighting measures
Fire and explosive properties: Combustible. Will burn at high temperatures.
Extinguishing media: Use water spray, ABC dry chemical, foam, or carbon dioxide. Use water to keep fire-exposed containers cool. Water spray may be used to flush spills away from exposures.
Fire-fighting instructions: Wear self-contained breathing apparatus (SCBA) equipped with a full-face piece and operated in a pressure-demand mode (or other positive pressure mode) and approved protective clothing. Personnel without suitable respiratory protection must leave the area to prevent significant exposure to hazardous gases from combustion, burning, or decomposition. In an enclosed or poorly ventilated area, wear SCBA during cleanup immediately after a fire as well as during the attack phase of fire-fighting operations.
Unusual fire/explosion hazards: Irritating or toxic substances may be emitted upon burning, combustion or decomposition.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6 - Accidental release measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment, cleanup procedures, and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and move to an approved disposal container. Avoid open flames or other sources of ignition.
7 - Handling and storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong acids and oxidizing agents. Storage: Room Temperature. Preferably refrigerate 2C to 8C. OK to freeze. Shipping may be ambient. Avoid light and moisture.
Fire Protection: Keep away from ignition sources and naked flame. Keep away from heat, sparks, and open flames.
8 - Exposure controls / personal protection
Exposure Limits: Not established.
Respiratory Protection: Avoid breathing directly on the product. Apply local ventilation when appropriate.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9 - Physical and chemical propertiesAppearance: White to off-white powder or crystals. Hygroscopic.
Odor: Odorless.
Odor threshold: Not applicable.
pH: No data found.
Relative density: No data found.
Boiling point C: 249C literature.
Melting point: 217C literature.
Flash point: No data found.
Auto-ignition temperature: Not available.No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate:No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility(ies): Slightly soluble in water; very slightly soluble in anhydrous ethanol; practically insoluble in acetone. It dissolves in dilute solutions of acids and of alkali hydroxides.
Viscosity: No data found.
10 - Stability and reactivity
Stability: This product is stable under recommended conditions of use and storage.
Hazardous polymerization: Hazardous polymerization will not occur.
Conditions to avoid: Excessive heat and ignition sources.
Incompatibility with other materials: Avoid contact with strong oxidizing agents and acids.
Hazardous decomposition products: Carbon dioxide and carbon monoxide.
11 - Toxicological information
LD50 Oral:No data found.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: No data found.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.
12 - Ecological information
Toxicity to fish: No data found.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative, and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
13 - Disposal information
Incinerate waste product when in liquid form (i.e., as supplied) in a properly permitted (approved) incineration facility in accordance with local regulations. Follow all the pollution control rules.
14 - Transportation information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA/ICAO: Not dangerous goods.
15 - Regulatory information
USA:
USA - California Proposition 65: Not listed for cancer or reproductive harm.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Ammonium Glycyrrhizate or Ammonium Glycyrrhizinate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- November 11, 2026
If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
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