Specifications, Uses, SDS of Dimeticone Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Dimethicone USP NF Dimeticone BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 9006-65-9 or 9006-75-9 or 9016-00-6 or 63148-62-9.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Dimethicone for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

Dimethicone or Dimeticone Manufacturer Supplier Exporter

Dimethicone or Dimeticone CAS Number 9006-65-9 or 9006-75-9 or 9016-00-6 or 63148-62-9

The Properties, Specifications, Monograph and Uses of Dimethicone or Dimeticone:

Dimethicone or Dimeticone is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations. Dimethicone is a silicone-based ingredient used in many personal care products. It keeps all of the ingredients in a product from separating. It also gives these products a smooth, silky texture.

Specifications of Dimethicone USP NF Grade:
α-(Trimethylsilyl)-ω-methylpoly[oxy(dimethylsilylene)] CAS 9006-65-9.

DEFINITION
Dimethicone is a mixture of fully methylated linear siloxane polymers containing repeating units of the formula: [–(CH3)2SiO–]n stabilized with trimethylsiloxy end-blocking units of the formula: [(CH3)3SiO–]
wherein n has an average value such that the corresponding nominal viscosity is in a discrete range between 20 and 30,000 centistokes. It contains NLT 97.0% and NMT 103.0% of polydimethylsiloxane ([–(CH3)2SiO–]n).
The requirements for viscosity, specific gravity, refractive index, and loss on heating differ for the several types of Dimethicone, as set forth in Table 1.

IDENTIFICATION
A. The IR absorption spectrum of the Sample exhibits maxima only at the same wavelengths as that of the Standard, obtained as directed in the Assay.

ASSAY
To pass the test by Mid-Infrared Spectroscopy.
Acceptance criteria: percentage of polydimethylsiloxane ([–(CH3)2SiO–]n) in the Dimethicone 97.0%–103.0%

Specific Gravity: See Table 1.
Refractive Index: See Table 1.
Acidity:
Sample: 15.0 g.
Analysis: Dissolve the Sample in a mixture of 15 mL of toluene and 15 mL of butyl alcohol, previously neutralized to bromophenol blue TS, and titrate with 0.050 N alcoholic potassium hydroxide to a bromophenol blue endpoint.
Acceptance criteria: NMT 0.10 mL of 0.050 N alcoholic potassium hydroxide is required.
Loss on Heating:
Sample: 1 g
Analysis: Preheat an open aluminum vessel (60 mm in diameter and 10 mm high) at 150C for 30 minutes, and allow to cool to room temperature. Tare the vessel, transfer the Sample to it, heat at 150C in a circulating air oven for 2 h, and allow to come to room temperature in a desiccator before weighing.
Acceptance criteria: See Table 1.

Bacterial Endotoxins Test: (where it is intended for use in coating containers that come in contact with articles for parenteral use)
Sample: 1.0 mL
Analysis: Mix the Sample with 4.0 mL of polydimethylsiloxane having a viscosity of 0.65 centistokes, previously tested and shown to be negative for bacterial endotoxins, by mixing on a vortex mixer for 1 min in an extraction tube. Add 10 mL of water, and mix on a vortex mixer for NLT 60 min. Allow the layers to separate, and use the lower aqueous layer as the sample.
Acceptance criteria: It contains NMT 1.0 USP Endotoxin Unit/mL, equivalent to NMT 10 Endotoxin Units/mL of the Dimethicone taken.
Viscosity—Capillary Methods and Viscosity—Rotational Methods:
Analysis: Determine the viscosity of Dimethicone having a nominal viscosity of less than 1000 centistokes at 25 ± 0.1°, using a capillary viscometer. Determine the viscosity of Dimethicone having a nominal viscosity of 1000 centistokes or greater at 25 ± 0.1°, using a rotational viscometer.
Acceptance criteria: See Table 1.
Packaging and Storage: Preserve in tight containers.

Specifications of Dimeticone BP Grade
Ph Eur --- 9006-75-9
Action and use: Antifoaming agent; water repellent. When dimethicone is demanded, Dimeticone shall be supplied.

DEFINITION
Poly(dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. Different grades of dimeticone exist which are distinguished by a number indicating the nominal kinematic viscosity placed after the name.
Their degree of polymerisation (n = 20 to 400) is such that their kinematic viscosities are nominally between 20 mm2.s-1 and 1300 mm2.s-1.
Dimeticones with a nominal viscosity of 50 mm2.s-1 or lower are intended for external use only.

CHARACTERS
Appearance: Clear, colourless liquid of various viscosities.
Solubility: Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.

IDENTIFICATION
A. It is identified by its kinematic viscosity at 25C (see Tests).
B. Infrared absorption spectrophotometry.
C. Heat 0.5 g in a test-tube over a small flame until white fumes begin to appear. Invert the tube over a 2nd tube containing 1 ml of a 1 g/l solution of chromotropic acid sodium salt in sulphuric acid so that the fumes reach the solution. Shake the 2nd tube for about 10 s and heat on a water-bath for 5 min. The solution is violet.
D. In a platinum crucible, prepare the sulphated ash using 50 mg. The residue is a white powder that gives the reaction of silicates.

TESTS
Acidity: To 2.0 g add 25 ml of a mixture of equal volumes of anhydrous ethanol and ether, previously neutralised to 0.2 ml of bromothymol blue solution and shake. Not more than 0.15 ml of 0.01 M sodium hydroxide is required to change the colour of the solution to blue.
Viscosity: 90 per cent to 110 per cent of the nominal kinematic viscosity stated on the label, determined at 25C.
Mineral oils: Place 2 g in a test-tube and examine in ultraviolet light at 365 nm. The fluorescence is not more intense than that of a solution containing 0.1 ppm of quinine sulphate in 0.005 M sulphuric acid examined in the same conditions.
Phenylated compounds: Dissolve 5.0 g with shaking in 10 ml of cyclohexane. At wavelengths from 250 nm to 270 nm, the absorbance of the solution is not greater than 0.2.
Heavy metals: Maximum 5 ppm.
Volatile matter: Maximum 0.3 per cent, for dimeticones with a nominal viscosity greater than 50 mm2.s-1, determined on 1.00 g by heating in an oven at 150C for 2 h. Carry out the test using a dish 60 mm in diameter and 10 mm deep.

Dimeticone or Dimethicone SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 28-Jun-21

Product Name & Other Names: Dimeticone or Dimethicone or Poly(dimethylsiloxane)
CAS Number: 9006-75-9 or 9016-00-6 or 63148-62-9
EINECS EC Code: Not available.
Recommended usage: Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Dimeticone or Dimethicone or Poly(dimethylsiloxane)
CAS Number: 9006-75-9

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: It is flammable on heating.
Products of Combustion: Oxides of Carbon, Silicone, and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids.

Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Clear liquid.
Odor: mild.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.94 to 0.97
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.

Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Heat.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents, acids, and bases.
Polymerization: Will not occur.

LD50 Oral - Rat - >1000 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: LC50 - Oncorhynchus mykiss (rainbow trout) - > 10,000 mg/l - 96 h.
BOD5 and COD: Not available.
Products of Biodegradation: The product itself and its products of degradation are not toxic.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMDG/IMO: Not dangerous goods.
Air Transport IATA/ICAO: Not dangerous goods.

USA Regulations:
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
SARA 311/312 Hazards: See section 2.

Dimethicone or Dimeticone Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Nominal Viscosity & Loss on heating	viscosity(centistokes)	Specific gravity	Refractive index
(centistokes)	Min. to Max.	Min. to Max.	Min. to Max.
020 ------ Max. 20.0	18 to 22	0.946 to 0.954	1.3980 to 1.4020
050 ------ Max. 2.0	47.5 to 52.5	0.955 to 0.965	1.4005 to 1.4045
100 ------ Max. 0.3	95 to 105	0.962 to 0.970	1.4005 to 1.4045
200 ------ Max. 0.3	190 to 220	0.964 to 0.972	1.4013 to 1.4053
350 ------ Max. 0.3	332.5 to 367.5	0.965 to 0.973	1.4013 to 1.4053
500 ------ Max. 0.3	475 to 525	0.967 to 0.975	1.4013 to 1.4053
1000 ---- Max. 0.3	950 to 1050	0.967 to 0.975	1.4013 to 1.4053
12,500 -- Max. 2.0	11,875 to 13,125	-- --	1.4015 to 1.4055
30,000 -- Max. 2.0	27,000 to 33,000	0.969 to 0.977	1.4010 to 1.4100

Specifications, Properties, Uses, SDS of Dimethicone USP NF Dimeticone BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 9006-65-9 or 9006-75-9 or 9016-00-6 or 63148-62-9.

Dimethicone or Dimeticone Manufacturers, Suppliers, Exporters, Wholesalers: