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King of Chemicals Manufacturers Prochlorperazine Maleate or Prochlorperazine Dimaleate and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of Prochlorperazine Maleate or Prochlorperazine Dimaleate API BP Ph Eur EP USP Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 84-02-6. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Prochlorperazine Maleate or Prochlorperazine Dimaleate BP Ph Eur EP USP Grade for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Prochlorperazine Maleate or Prochlorperazine Dimaleate CAS Number 84-02-6
For Properties Specifications Uses of Prochlorperazine Maleate or Prochlorperazine Dimaleate Click Properties, Specifications, Uses, Price, Process of Prochlorperazine Maleate or Prochlorperazine Dimaleate Manufacturer.
For For SDS MSDS Sheet of Prochlorperazine Maleate or Prochlorperazine Dimaleate Click SDS Safety Data Sheet MSDS Sheet of Prochlorperazine Maleate or Prochlorperazine Dimaleate Manufacturer.
The Properties, Specifications, Monograph and Uses of Prochlorperazine Maleate or Prochlorperazine Dimaleate:
Prochlorperazine maleate is a prescription medication belonging to the phenothiazine class of first-generation (typical) antipsychotics. While originally developed as a neuroleptic, it works by blocking dopamine D2 receptors in the brain and central nervous system, making it highly effective for a wide variety of medical conditions. It is used in medecine for Severe Nausea and Vomiting, Vertigo and Inner Ear Disorders, Acute Migraine Headaches, Non-Psychotic Generalized Anxiety, Psychiatric Conditions, etc.
Prochlorperazine Maleate BP Ph Eur Grade:
C28H32ClN3O8S --- 606 CAS 84-02-6
Action and use: Dopamine receptor antagonist; neuroleptic.
DEFINITION
2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine bis[hydrogen (Z)-butenedioate].
Content: 98.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or pale-yellow, crystalline powder.
Solubility: Very slightly soluble in water and in ethanol (96 per cent).
IDENTIFICATION
First identification: B, C, D
Second identification: A, C, D
A. Ultraviolet and visible absorption spectrophotometry.
B. Infrared absorption spectrophotometry.
C. Identification test for phenothiazines by thin-layer chromatography.
D. Triturate –
TESTS
pH: 3.0 to 4.0 for a freshly prepared saturated solution in carbon dioxide-free water.
Related substances: To pass the test by Thin-layer chromatography.
Loss on drying: Maximum 1.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Storage: Protected from light.
Prochlorperazine Maleate USP Grade:
C20H24ClN3S-2C4H4O4 --- 606.09
10H< -Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, (Z)-2-butenedioate (1:2);
2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine maleate (1:2)
CAS 84-02-6
UNII: I1T8O1JTL6
UNII: YHP6YLT61T
DEFINITION
Prochlorperazine Maleate contains NLT 98.0 and NMT 102.0% of prochlorperazine maleate (C20H24ClN3S-2C4H4O4), calculated on the dried basis.
[Note: Throughout the following procedures, protect the samples, the Reference Standard, and solutions containing them from light, and conduct the procedures without delay.]
IDENTIFICATION
A. Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution.
Assay: 98% to 102%
Residue on Ignition: NMT 0.1%
Organic Impurities: To pass the test by chromatography.
Loss on Drying: Dry under vacuum at 60° for 2 h. Acceptance criteria: NMT 0.5%
Packaging and Storage: Preserve in tight, light-resistant containers. Store at room temperature.
Prochlorperazine Dimaleate or Prochlorperazine Maleate EP Grade is also manufactured.
The MSDS-SDS Hazard Statement of Prochlorperazine Maleate or Prochlorperazine Dimaleate:
Prochlorperazine Dimaleate or Prochlorperazine Maleate
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: Prochlorperazine Dimaleate or Prochlorperazine Maleate.
CAS No.: 84-02-6
EINECS EC-No.: 201-511-3
Chemical Formula: C28H32ClN3O8S
Molecular Weight: 606.09
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral Category 4 - H302
Acute toxicity, dermal Category 4 - H312
Acute toxicity, inhalation Category 4 - H332
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Harmful |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H332: Harmful if inhaled.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Prochlorperazine Dimaleate or Prochlorperazine Maleate.
CAS No.: 84-02-6
EINECS EC-No.: 201-511-3
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Auto ignition temperature: High heat or direct flame is necessary to cause ignition.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, sand, or carbon dioxide. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Avoid solid stream of water. Water spray may be used to keep fire exposed containers cool. Carbon dioxide and carbon monoxide, Nitrogen oxides (NOx) Sulfur oxides, Hydrogen cyanide, Chlorine compounds will be formed on combustion.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Pick up and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Finish cleaning by spreading water on the contaminated surface and dispose as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong acids, and bases. Store at room temperature 20C to 25C. Protect from light. Dispense in a tight, light-resistant container. (Recommended in a cool and dark place, <15C).
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established by any regulating body.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): Use only under a chemical fume hood. For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White or pale-yellow, crystalline powder.
Odor:No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Boiling Point:No data found.
Melting Point: 187C to 190 commonly cited in literature. 194C is also reported.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor Density (Air=1): No data found.
Vapor Pressure (mm Hg):No data found.
Evaporation Rate (BuAc=1): No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Very slightly soluble in water and in ethanol (96 per cent). Soluble in organic solvents like DMSO, Diethyl ether.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide, Nitrogen oxides (NOx), Sulfur oxides, Chlorine compounds may form when heated to decomposition.
Hazardous Polymerization: Not reported.
Incompatibilities: Strong oxidizing agents, Strong acids, and bases.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles. Avoid dust formation, Excess heat. Exposure to light and Exposure to moisture. Risk of ignition or formation of inflammable gases or vapors with chlorite.
11. Toxicological Information
Oral rat LD50: 750 mg/kg.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC, ACGIH, OSHA, NTP.
12. Ecological Information
Toxicity to fish: No data found.
Persistence and Degradability: No data found.
Mobility: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312: See section 2
US California Proposition 65: Not listed.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Prochlorperazine Maleate or Prochlorperazine Dimaleate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- November 9, 2026
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If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
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