Specifications, Uses, SDS of Aspartame Manufacturers

	King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Aspartame USP NF BP Ph Eur EP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 22839-47-0.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals.

Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Aspartame for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

Aspartame is an artificial non-saccharide sweetener 200 times sweeter than sucrose and is commonly used as a sugar substitute in foods and beverages. It is a methyl ester of the aspartic acid/phenylalanine dipeptide. Aspartame is approved for use in food products by most countries. It has an E number of E951.

Aspartame USP NF Grade:
C14H18N2O5 --- 294.30
L-Phenylalanine, N-L- -aspartyl-, 1-methyl ester.
3-Amino-N-( -carboxyphenethyl)succinamic acid N-methyl ester --- CAS 22839-47-0.

Aspartame contains not less than 98.0 percent and not more than 102.0 percent of C14H18N2O5, calculated on the dried basis.

Identification: Do not dry specimens.
Transmittance: The transmittance of a 1 in 100 solution of it in 2 N hydrochloric acid, prepared by means of sonication, determined in a 1-cm cell at 430 nm with a suitable spectrophotometer, is not less than 0.95, corresponding to an absorbance of not more than about 0.022.
Specific rotation: between +14.5 and +16.5 , determined at 20 within 30 minutes after preparation of the solution.
Test solution: 40 mg per mL, in 15 N formic acid.
Loss on drying: Dry it at 105 for 4 hours: it loses not more than 4.5% of its weight.
Residue on ignition: not more than 0.2%.
Heavy metals: 0.001%.
Limit of 5-benzyl-3,6-dioxo-2-piperazineacetic acid: To pass the test.
Chromatographic purity: To pass the test --- corresponding to not more than 2.0% of chromatographic impurities.

Specifications of Aspartame BP Ph Eur Grade:
C14H18N2O5 --- 294.3 --- CAS 22839-47-0
Action and use: Sweetening agent.

DEFINITION
(3S)-3-Amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid (methyl α-L-aspartyl-L-phenylalaninate).
Content: 98.0 per cent to 102.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, slightly hygroscopic, crystalline powder.
Solubility: Sparingly soluble or slightly soluble in water and in ethanol (96 per cent), practically insoluble in hexane and in methylene chloride.

IDENTIFICATION
First identification: B
Second identification: A, C, D
A. Ultraviolet and visible absorption spectrophotometry.
B. Infrared absorption spectrophotometry.
C. Thin-layer chromatography.
D. Dissolve about 20 mg in 5 mL of methanol and add 1 mL of alkaline hydroxylamine solution. Heat on a water-bath for 15 min. Allow to cool and adjust to about pH 2 with dilute hydrochloric acid. Add 0.1 mL of ferric chloride solution. A brownish-red colour is produced.

TESTS
Solution S: Dissolve 0.8 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Conductivity: Maximum 30 microS/cm. To pass the test.
Specific optical rotation: + 14.5 to + 16.5 (dried substance).
Related substances: To pass the test.
Loss on drying: Maximum 4.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.2 per cent, determined on 1.0 g.

Specifications of Aspartame FCC Food Grade:
N-L-alpha-Aspartyl-L -phenylalanine 1-Methyl Ester; APM
C14H18N2O5 Formula weight 294.31
INS: 951 CAS 22839-47-0

DESCRIPTION
Aspartame occurs as a white, crystalline powder. It is sparingly soluble in water and slightly soluble in alcohol. The pH of a 0.8% solution is between about 4.5 and 6.0.
Function: Sweetener; sugar substitute; flavor enhancer.

Aspartame or Asp-Phe methyl ester SDS Sheet, Safety Data Sheet
MSDS, Material Safety Data Sheet 02-Oct-20

Product Name & Other Names: Aspartame or Asp-Phe methyl ester.
CAS No.: 22839-47-0
EINECS EC Code: 245-261-3
Molecular Weight: 294.31
Chemical Formula: C14H18N2O5
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Aspartame or Asp-Phe methyl ester.
CAS No.: 22839-47-0
EINECS EC Code: 245-261-3

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

Combustible at high temperature. High heat or direct flame is necessary to cause ignition. Toxic fumes, carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: At high temperature, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, water spray or carbon dioxide. Do not use a solid stream of water since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cold, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material.

Airborne Exposure Limits: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White solid.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Melting point: 246C - 247C
Boiling point: Decomposes.
Relative density: 1.35
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Sparingly soluble; Slightly soluble in ethanol.
Viscosity: Not available.
Molecular Weight: 294.31
Chemical Formula: C14H18N2O5.

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, sunlight, ignition sources and incompatibles.

Oral rat LD50: > 10.000 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: No data found.
Mutagenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.

Toxicity to fish: No information available.
Mobility: Likely to be mobile.
Biodegradability: Readily biodegradable
Results of PBT and vPvB assessment: No data available for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

Land Transport DOT USA TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMO/IMDG: Not dangerous goods.
Air Transport ICAO/IATA: Not dangerous goods.

USA:
SARA 311/312 Hazards: See section 2.
California Prop. 65 Components: Not listed.

Aspartame Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individual.

Specifications, Properties, Uses, SDS of Aspartame USP NF BP Ph Eur EP FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 22839-47-0.

Aspartame Manufacturers, Suppliers, Exporters, Wholesalers: