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King of Chemicals Manufacturers Menadione or Vitamin K3 and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of Menadione or Vitamin K3 BP Ph Eur USP Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 58-27-5. | |
| King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer API USP NF BP Ph Eur EP IP JP ChP PPRC Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Menadione or Vitamin K3 BP Ph Eur USP Grade for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Menadione or Vitamin K3 CAS Number 58-27-5
For Properties Specifications Uses of Menadione or Vitamin K3 Click Properties, Specifications, Uses, Price, Process of Menadione or Vitamin K3 Manufacturer.
For For SDS MSDS Sheet of Menadione or Vitamin K3 Click SDS Safety Data Sheet MSDS Sheet of Menadione or Vitamin K3 Manufacturer.
The Properties, Specifications, Monograph and Uses of Menadione or Vitamin K3:
Menadione or Vitamin K3 is a synthetic form of vitamin K primarily used to treat vitamin K deficiency and prevent severe hypoprothrombinaemia. Because of its coagulant property, it plays a vital role in helping the blood clot properly. In the United States, menadione is used in various types of animal feed and is described as having a history of safe use for this purpose.
Menadione BP Ph Eur Grade Specifications:
C11H8O2 --- 172.2 --- CAS 58-27-5
Action and use: Vitamin K analogue.
DEFINITION
Menadione contains not less than 98.5 per cent and not more than the equivalent of 101.0 per cent of 2-methylnaphthalene-1,4-dione, calculated with reference to the dried substance.
CHARACTERS
A pale-yellow, crystalline powder, practically insoluble in water, freely soluble in toluene, sparingly soluble in alcohol and in methanol. It is unstable in light.
IDENTIFICATION
First identification: A, B
Second identification: A, C, D
A. Melting point: 105C to 108C.
B. Infrared absorption spectrophotometry.
C. Dissolve about 1 mg in 5 mL of alcohol, add 2 mL of ammonia and 0.2 mL of ethyl cyanoacetate. An intense bluish-violet colour develops. Add 2 mL of hydrochloric acid. The colour disappears.
D. Dissolve about 10 mg in 1 mL of alcohol, add 1 mL of hydrochloric acid and heat in a water-bath. A red colour develops.
TESTS
Related substances: To pass the test by thin-layer chromatography.
Loss on drying: Not more than 0.5 per cent, determined on 1.000 g by drying over diphosphorus pentoxide at a pressure of 2 kPa to 3 kPa for 4 h.
Sulfated ash: Not more than 0.1 per cent, determined on 1.0 g.
Menadione USP Grade Specifications:
C11H8O2 --- 172.18
1,4-Naphthalenedione, 2-methyl-;
2-Methyl-1,4-naphthoquinone --- CAS 58-27-5
UNII: 723JX6CXY5
DEFINITION
Menadione contains NLT 98.5% and NMT 101.0% of menadione (C11H8O2),calculated on the dried basis.
[Caution— Menadione powder is irritating to the respiratory tract and to the skin, and a solution of it in alcohol is a vesicant. ]
IDENTIFICATION
A. Infrared Absorption
B. Ultraviolet Absorption
Residue on Ignition: NMT 0.1%
Ordinary Impurities: To pass the test.
Loss on Drying: Dry over silica gel for 4 h. NMT 0.3%
Packaging and Storage: Preserve in well-closed, light-resistant containers. Store at 25°, excursions permitted between 15° and 30°.
The MSDS-SDS Hazard Statement of Menadione or Vitamin K3:
Menadione or Vitamin K3 or 2-Methyl-1,4-naphthoquinone
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: Menadione or Vitamin K3 or 2-Methyl-1,4-naphthoquinone.
CAS No.: 58-27-5
EINECS EC Number: 200-372-6
Molecular Formula: C11H8O2
Molecular Weight: 172.18
Relevant uses and uses advised against (if any): Laboratory and Industrial Use.
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4, H302
Skin corrosion/irritation Category 2, H315
Skin sensitization, Category 1, H317
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Hazardous to the aquatic environment, long-term hazard Category 1, H410
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Aquatic Toxicity | GHS Label Elements Irritant Harmful |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H317: May cause an allergic skin reaction.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H410: Very Toxic to aquatic life with long lasting effects.
Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get medical advice/attention if you feel unwell.
P330: Rinse mouth.
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362: Take off contaminated clothing and wash before reuse.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P391: Collect spillage.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.
3. Composition/Information on Ingredients
Product Name & Other Names: Menadione or Vitamin K3 or 2-Methyl-1,4-naphthoquinone.
CAS No.: 58-27-5
EINECS EC Number: 200-372-6
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reusing. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Carbon dioxide, Carbon monoxide, Fumes.
Explosion: Slightly explosive in presence of heat.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures or when moistened under fire conditions, it may produce toxic or irritating fumes. On decomposition it may emit toxic fumes. Containers may explode on heating.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Avoid touching the spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Do not contaminate the environment.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions or safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, reducing agents, metals, and acids. Storage: Preserve in well-closed, light-resistant containers. Store at 25°, excursions permitted between 15° and 30°.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established by regulating bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: Bright yellow solid.
Odor: Very mild acrid odor.
Odor threshold: No data found.
pH: No data found.
Relative density: about 1.38
Boiling Point: No data found.
Melting Point: about 105C to 107C literature.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Very slight solubility in water. Soluble in ethyl ether, benzene, and chloroform.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: It emits Carbon dioxide, Carbon monoxide, Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, reducing agents, metals, and acids.
Conditions to Avoid: Incompatibles and moisture and heat.
11. Toxicological Information
Toxicity data
ORL-RAT LD50 500 mg kg-1
ORL-Mouse LD50 500 mg kg-1
Carcinogenic Effects: Not known as carcinogen.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found.
12. Ecological Information
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) – 0.31 mg/l - 48 h
Persistence and Degradability: No data found.
Mobility: No data found.
Bioaccumulation/ Accumulation: No data found.
Results of PBT and vPvB assessment: No data found.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules.
14. Transport Information
USA DOT & ADR/RID Europe Classification:
UN number: 3077
UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (menadione)
Transport hazard class(es): 9
Packaging group: III.
Canada TDG Classification:
UN number: 3077
UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (menadione)
Transport hazard class(es): 9
Packaging group: III.
IMDG & IATA
UN number: 3077
UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (menadione)
Transport hazard class(es): 9
Packaging group: III.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California prop. 65: Not listed.
Section 16 - Additional Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Menadione or Vitamin K3 Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- October 31, 2026
If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
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