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King of Chemicals Manufacturers Anagrelide Hydrochloride or Anagrelide HCl and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of Anagrelide Hydrochloride or Anagrelide HCl API USP Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 58579-51-4 Anhydrous, 823178-43-4 Monohydrate. | |
| King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer API USP NF BP Ph Eur EP IP JP ChP PPRC Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Anagrelide Hydrochloride or Anagrelide HCl USP Grade for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Anagrelide Hydrochloride or Anagrelide HCl CAS Number 58579-51-4 Anhydrous, 823178-43-4 Monohydrate
For Properties Specifications Uses of Anagrelide Hydrochloride or Anagrelide HCl Click Properties, Specifications, Uses, Price, Process of Anagrelide Hydrochloride or Anagrelide HCl Manufacturer.
For For SDS MSDS Sheet of Anagrelide Hydrochloride or Anagrelide HCl Click SDS Safety Data Sheet MSDS Sheet of Anagrelide Hydrochloride or Anagrelide HCl Manufacturer.
The Properties, Specifications, Monograph and Uses of Anagrelide Hydrochloride or Anagrelide HCl:
Anagrelide hydrochloride is a platelet-reducing medication primarily used to treat thrombocythemia. Its medical uses include Essential Thrombocythemia, Other Myeloproliferative Disorders, etc.
Anagrelide Hydrochloride USP Grade Specifications:
C10H7Cl2N3O-HCl-H2O --- 310.56
Anhydrous 292.55 CAS 58579-51-4
Imidazo[2,1-b]quinazolin-2(3H)-one, 6,7-dichloro-1,5-dihydro-, monohydrochloride, monohydrate;
6,7-Dichloro-1,5-dihydroimidazo[2,1-b]-quinazolin-2(3H)-one monohydrochloride, monohydrate CAS 823178-43-4.
UNII: VNS4435G39
UNII: K9X45X0051
DEFINITION
Anagrelide Hydrochloride contains NLT 98.0% and NMT 102.0% of anagrelide hydrochloride (C10H7Cl2N3O-HCl), calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption.
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
C. Identification Tests—General, Chloride: Meets the requirements.
Assay: 98% to 102% on the anhydrous basis.
Residue on Ignition: NMT 0.1%
Organic Impurities: To pass the test by chromatography.
Water Determination: 4.5%–7.5%
Packaging and Storage: Preserve in tight, light-resistant containers. Store in a cold place.
The MSDS-SDS Hazard Statement of Anagrelide Hydrochloride or Anagrelide HCl:
Anagrelide Hydrochloride or Anagrelide HCl SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: Anagrelide Hydrochloride or Anagrelide HCl.
CAS No.: 58579-51-4 Anhydrous, 823178-43-4 Monohydrate
EINECS EC Number: 680-360-9
Molecular Weight: 292.55 Anhydrous
Chemical Formula: C10H7Cl2N3O-HCl Anhydrous
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4, H302
Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Irritant Harmful |
Signal Words: Warning
Hazard statements:
H302: Harmful if swallowed
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Anagrelide Hydrochloride or Anagrelide HCl.
CAS No.: <58579-51-4 Anhydrous, 823178-43-4 Monohydrate
EINECS EC Number: 680-360-9
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire: May become a fire hazard at high temperatures.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet as it can scatter the fire.
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Sulfur oxides, Hydrogen chloride gas.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Avoid dust formation and control ignition sources. Storage: Room Preserve in tight, light-resistant containers. Store in a cold place. Refrigerate (2C to 8C.). Short term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control for this substance. However, if conditions of use create discomfort to the worker, a local exhaust system should be considered.
Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White to beige powder.
Odor:No data found.
Odor threshold: No data found.
pH: No data found.
Relative density: No data found.
Boiling Point:No data found.
Melting Point: >280C literature.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Very slightly soluble in water. Slightly soluble in DMSO and dimethylformamide DMF, and insoluble in ethanol.
Viscosity: No data found.
10. Stability and Reactivity
Stability: It is stable under recommended conditions of use and storage.
Hazardous Decomposition Products: May produce oxides of nitrogen, sulfur and carbon along with chlorine compounds and fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flame, ignition sources, light, dusting and incompatibles.
11. Toxicological Information
LD50 oral rat: No data found.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Germ cell mutagenicity: No data found.
Reproductive toxicity: No data found.
12. Ecological Information
Toxicity: Acute Toxicity RAT-ORL LD50: >1500mg/kg.
Persistence and degradability: Unlikely to persist due to water solubility.
Bioaccumulative potential: No data found.
Mobility: Likely to be mobile due to water solubility.
Results of PBT and vPvB assessment: Not PBT or vPvB.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IATA/ICAO: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312 Hazardous Categorization: See section 2.
California Proposition 65: Not listed.
16. Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Anagrelide Hydrochloride or Anagrelide HCl Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- November 3, 2026
If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
| We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. | |
Anagrelide Hydrochloride or Anagrelide HCl | |