Specifications, Uses, SDS of Meglumine USP BP Ph Eur Manufacturers

	King of Chemicals
Specifications, Properties, Uses, SDS of Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol USP BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 6284-40-8.
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Meglumine for actual users, including retail or small pack supplies for research and development work.

We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.

Meglumine Manufacturer Supplier Exporter

Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol CAS Number 6284-40-8

The Properties, Specifications, Monograph and Uses of Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol:

Meglumine, USP is used as a functional excipient where it acts as a counterion to enhance API stability and solubility. 1. N-Methyl-D-glucamine or Meglumine can be used as a contrast agent and surfactant for medical use. It is also used as an excipient in pharmaceuticals, in cosmetics and X-ray contrast media. It is also employed in the synthesis of surface active agents, pharmaceuticals and dyes.Meglumine is a sugar alcohol derived from glucose that contains an amino group modification.

General Properties and Specifications of N-methyl d-glucamine or Meglumine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol:
Appearance: White crystalline powder.
Purity: 99.0%-100.5%
Loss on drying: 1% maximum.
Residue on ignition: 0.1% maximum.
Heavy metals: 20 ppm maximum.
Melting point: 128C to 132C.
Solubility: Soluble in water.

Meglumine USP Grade Specifications:
C7H17NO5 --- 195.21
d-Glucitol, 1-deoxy-1-(methylamino)-;
1-Deoxy-1-(methylamino)-d-glucitol CAS 6284-40-8.

DEFINITION
Meglumine contains NLT 99.0% and NMT 100.5% of meglumine (C7H17NO5), calculated on the dried basis.

IDENTIFICATION
A.
Sample solution: Transfer 250 mg to a dry, 50-mL centrifuge tube, add 500 mg of sodium metaperiodate, then add 5 mL of water rapidly in one portion. Allow to stand undisturbed.
Analysis: The solution instantly turns yellow, and heat is produced. The color then changes from deep yellow to orange-brown (rust), and after 20 min, the rust-colored solution is cloudy. Then add 2 mL of 2.5 N sodium hydroxide.
Acceptance criteria: The mixture turns bright yellow and becomes clear.

Residue on Ignition: NMT 0.1%
Absence of Reducing Substances
Sample solution: 50 mg/mL
Analysis: To 5 mL of Sample solution add 5 mL of alkaline cupric tartrate TS, and heat to boiling.
Acceptance criteria: The color of the solution does not change.
Completeness and Color of Solution: To pass the test.
Loss on Drying: NMT 1.0% at 105C to constant weight.
Melting Range or Temperature: 128C to 132C.
Optical Rotation, Specific Rotation:
Sample solution: 100 mg/mL, undried, in water.
Acceptance criteria: -15.7° to -17.3°
Packaging and Storage: Preserve in well-closed containers.

Meglumine BP Ph Eur Grade Specifications:
C7H17NO5 --- 195.2 --- CAS 6284-40-8
Action and use: Organic base used in the preparation of organic acids.

DEFINITION
1-Deoxy-1-(methylamino)-D-glucitol.
Content: 99.0 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
Mp: About 128C.

IDENTIFICATION
Infrared absorption spectrophotometry: Comparison meglumine CRS.

The MSDS-SDS Hazard Statement of Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol:

Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol SDS, Safety Data Sheet
MSDS Sheet 19-Apr-22

Product Name & Other Names: Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol.
CAS Number: 6284-40-8
EINECS EC Code: 228-506-9
Molecular Formula: C7H17NO5
Molecular Weight: 195.21
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol.
CAS Number: 6284-40-8
EINECS EC Code: 228-506-9

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: Flammable in high concentration of dust in air.
Products of Combustion: Carbon oxides, Nitrogen oxides (NOx) and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Wear self-contained breathing apparatus for firefighting if necessary.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At elevated temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cold, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Do not store with incompatible materials like oxidizing agents. Hygroscopic. Air sensitive.

Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Engineering Controls: Showers, Eyewash stations and Ventilation systems
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice.

Physical state and appearance: White crystalline powder.
Odor: Not available.
Odor threshold: Not available.
pH (5% soln/water): Not available.
Relative density: Not available.
Melting point/freezing point: 128C to 132C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water. Sparingly soluble in ethanol (96 per cent). Practically insoluble in methylene chloride.
Viscosity: Not available.
Molecular Formula: C7H17NO5
Molecular Weight: 195.21

Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture. Hygroscopic. Air sensitive.
Incompatibility with various substances: Avoid elevated temperatures, sparks, open flames. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.

LD50 Oral Rat: >5000 mg/kg.
LD50 Oral Rabbit: >5000 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: Not available.
Persistence and Degradability: It is expected to be degradable.
Mobility: Likely to be mobile.
Results of PBT and vPvB assessment: No data available for assessment.

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
Sea Transport IMDG/IMO: Not Regulated.
Air Transport IATA/ICAO: Not Regulated.

USA Regulations:
SARA 311/312: See section 2.
California Prop 65: None of the chemicals in this product are listed.

Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol Manufacturers, Suppliers, Exporters, Wholesalers:

Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564

If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo it

Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.

Specifications, Properties, Uses, SDS of Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol USP BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 6284-40-8.

Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol Manufacturers, Suppliers, Exporters, Wholesalers: