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King of Chemicals Manufacturers L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate and API BP Ph Eur EP USP NF IP JP ChP PPRC Reagent FCC Food Grade Manufacturer |
Specifications, Properties, Uses, SDS of L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate API BP Ph Eur EP FCC Food GradeManufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 5934-29-2. | |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of L-Histidine Hydrochloride Monohydrate for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, API IP BP USP Ph Eur EP JP ChP PPRC and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate CAS Number 5934-29-2
For Properties Specifications Uses of L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate Click Properties, Specifications, Uses, Price, Process of L-Histidine Hydrochloride Monohydrate Manufacturer.
For For SDS MSDS Sheet of L-Histidine Hydrochloride Monohydrate Click SDS Safety Data Sheet MSDS Sheet of L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate Manufacturer.
The Properties, Specifications, Monograph and Uses of L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate:
L-Histidine Hydrochloride Monohydrate is a highly water-soluble, stable salt form of L-histidine, an essential amino acid required by the human body. It serves crucial roles across the pharmaceutical, biotechnology, nutritional, and laboratory research industries. It is used in Biologic and Vaccine Stabilization, pH Buffering, Preventing Protein Aggregation, Nutritional Deficiency Treatment, Dermatological Treatment, Dietary Supplements & Food Industry, Animal Nutrition etc.
L-Histidine Monohydrochloride FCC Food Grade Specifications:
L-_-Amino-4(or 5)-imidazolepropionic Acid Monohydrochloride
C6H9N3O2-HCl-H2O Formula weight 209.63
CAS: monohydrate CAS 5934-29-2
DESCRIPTION
L-Histidine Monohydrochloride occurs as white crystals or as a crystalline powder. It is soluble in water, and insoluble in alcohol and in ether. It melts with decomposition at about 250C (after drying).
Function: Nutrient.
REQUIREMENTS
Identification: The infrared absorption spectrum of the sample exhibits relative maxima at the same wavelengths as those of a typical spectrum as shown in the section on Infrared Spectra, using the same test conditions as specified therein.
Assay: Not less than 98.5% and not more than 101.5% of C6H9N3O2·HCl·H2O, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 0.3%.
Optical (Specific) Rotation [α]D20°: Between +8.5° and +10.5°, calculated on the dried basis.
Residue on Ignition: Not more than 0.1%.
Histidine Hydrochloride Monohydrate BP Ph Eur Grade Specifications:
C6H10ClN3O2,H2O -- 209.6 -- CAS 5934-29-2
Action and use: Amino acid.
DEFINITION
(2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride monohydrate.
Product of fermentation or of protein hydrolysis.
Content: 98.5 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals.
Solubility: Freely soluble in water, slightly soluble in ethanol (96 per cent).
IDENTIFICATION
First identification: A, B, C, F
Second identification: A, B, D, E, F
A. Specific optical rotation.
B. pH.
C. Infrared absorption spectrophotometry.
D. Thin-layer chromatography.
E. Dissolve 0.1 g in 7 mL of water and add 3 mL of a 200 g/L solution of sodium hydroxide. Dissolve 50 mg of sulfanilic acid in a mixture of 0.1 mL of hydrochloric acid and 10 mL of water and add 0.1 mL of sodium nitrite solution. Add the second solution to the first and mix. An orange red colour develops.
F. About 20 mg gives reaction (a) of chlorides.
TESTS
Solution S: Dissolve 2.5 g in carbon dioxide-free water prepared from distilled water and dilute to 50 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 3.0 to 5.0 for solution S.
Specific optical rotation: + 9.2 to + 10.6 (dried substance).
Ninhydrin-positive substances: to pass the test.
Sulfates: Maximum 300 ppm.
Ammonium: to pass the test.
Iron: Maximum 10 ppm.
Loss on drying: 7.0 per cent to 10.0 per cent, determined on 1.000 g by drying in an oven at 145-150C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
We manufacture Histidine Hydrochloride Monohydrate or Histidine HCl Monohydrate EP BP Ph Eur FCC Food Grade
The MSDS-SDS Hazard Statement of L-Histidine Hydrochloride Monohydrateor L-Histidine HCl Monohydrate :
L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate.
CAS No.: 5934-29-2
EINECS: EC Number: 211-438-9 or 611-821-4
Molecular Weight: 209.63
Molecular Formula: C6H10N3O2Cl-H2O
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per letterhead above.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Serious eye damage/eye irritation Category 2A, H319
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Irritant |
Signal Words: Warning
Hazard statements:
H319: Causes serious eye irritation.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352-IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
3. Composition/Information on Ingredients
Product Name & Other Names: L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate.
CAS No.: 5934-29-2
EINECS: EC Number: 211-438-9 or 611-821-4
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: Not easily combustible. Combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Nitrogen oxides, carbon dioxide, carbon monoxide, chlorine or hydrochloric acid and toxic fumes.
Fire: Flammable in the presence of open flame.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Keep away from sources of ignition. Storage: Room temperature.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established by regulating bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures low.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White crystalline powder.
Odor: It has typical floral odor.
Odor threshold: No data found.
pH: 3.0 - 5.0 for 50g/l in CO₂-free water.
Relative density: No data found.
Boiling Point: No data found.
Melting Point: 254C.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Soluble in water.
Viscosity: No data found.
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: It emits Nitrogen oxides, carbon dioxide, carbon monoxide, chlorine or hydrochloric acid and toxic fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents.
Conditions to Avoid: Incompatibles, flame, heat & light.
11. Toxicological Information
Toxicity data
ORL-RAT LD50 >2000 mg/kg.
Carcinogenic Effects: No classification data on carcinogenic properties of this material is available from the EPA, IARC, NTP, OSHA or ACGIH.
Germ cell mutagenicity: No data found.
Reproductive toxicity: No data found.
Teratogenic Effects: No data found.
12. Ecological Information
Environmental Fate: No data found.
Environmental Toxicity: Not known.
Products of Biodegradation: Hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Persistence and degradability: Persistence is unlikely due to water solubility.
Bioaccumulative potential: No data found.
Mobility: Likely to be mobile due to water solubility.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Dispose of containers and unused contents in accordance with federal, state, and local requirements. Follow all the pollution control rules.
14. Transport Information
USA DOT Classification: Not gangerous goods.
Canada TDG Classification: Not gangerous goods.
IATA: Not gangerous goods.
ADR/RID Europe:Not gangerous goods.
IMDG: Not gangerous goods.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California prop. 65: Not listed.
Section 16 - Additional Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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L-Histidine Hydrochloride Monohydrate or L-Histidine HCl Monohydrate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-65290111
email: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- October 30, 2026
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If I sign an “Agreement” my Lawyer will undo it
Our products are for industrial and laboratory use only. The user must test the material before use. We are not despensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
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