King of Chemicals Manufacturers
Specifications, Properties, Uses, SDS of Calcium Dobesilate Monohydrate BP Ph Eur EP Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 20123-80-2.
King of Chemicals has several associated companies having accreditations like cGMP, GLP - FDA Approved Good Manufacturing Practice and Good Laboratory Practice of WHO standard, ISO-9001, ISO-14001, ISO/IEC 17025, ISO ISO-45000, HACCP, FSSC 220000, FSSAI, "REACH" Registered, Kosher & Halal Certified. e-CTD and DMF support can be made available if needed. We offer USP NF BP Ph Eur EP IP JP Analytical Reagent FCC Food Grade Chemicals & Nutraceuticals. Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Calcium Dobesilate Monohydrate BP Ph Eur EP for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Calcium Dobesilate Monohydrate CAS Number 20123-80-2For Properties Specifications Uses of Calcium Dobesilate Monohydrate Click Properties, Specifications, Uses, Price, Process of Calcium Dobesilate Monohydrate Manufacturer.
For For SDS MSDS Sheet of Calcium Dobesilate Monohydrate Click SDS Safety Data Sheet MSDS Sheet of Calcium Dobesilate Monohydrate Manufacturer.
The Properties, Specifications, Monograph and Uses of Calcium Dobesilate Monohydrate:
We manufacture Calcium Dobesilate Monohydrate BP Ph Eur EP Grade.
Calcium Dobesilate Monohydrate BP Ph Eur Grade Specifications
Ph. Eur.
C12H10CaO10S2-H2O --- 436.4 --- 20123-80-2DEFINITION
Calcium di(2,5-dihydroxybenzenesulfonate) monohydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).CHARACTERS
Appearance: White or almost white, hygroscopic powder.
Solubility: Very soluble in water, freely soluble in anhydrous ethanol, very slightly soluble in 2-propanol, practically insoluble in methylene chloride.IDENTIFICATION
A. Ultraviolet and visible absorption spectrophotometry.
B. Mix 1 mL of ferric chloride solution, 1 mL of a freshly prepared 10 g/L solution of potassium ferricyanide & and 0.1 mL of nitric acid R. To this mixture add 5 mL of freshly prepared solution S (see Tests): a blue colour and a precipitate are immediately produced.
C. 2 mL of freshly prepared solution S gives reaction of calcium.TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water ;and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S, when freshly prepared, is clear and colourless.
pH: 4.5 to 6.0 for solution S.
Related substances: To pass the test of Liquid chromatography
Iron: Maximum 10 ppm, determined on 10 mL of solution S.
Water: 4.0 per cent to 6.0 per cent, determined on 0.500 g.ASSAY
Dissolve 0.200 g in a mixture of 10 mL of water R and 40 mL of dilute sulfuric acid R. Titrate with0.1 M cerium sulfate, determining the end-point potentiometrically. 1 mL of 0.1 M cerium sulfat is equivalent to 10.45 mg of C12H10CaO10S2.STORAGE
In an airtight container, protected from light.IMPURITIES
Specified impurities A: benzene-1,4-diol (hydroquinone).
The MSDS-SDS Hazard Statement of Calcium Dobesilate Monohydrate:
Calcium Dobesilate Monohydrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 23-10-241. Product Identification
Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-2
Molecular Weight: 436.4
Chemical Formula: C12H10CaO10S2-H2O
Relevant Uses: Industrial use only.
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008Skin corrosion/irritation Category 2
Serious eye irritation/damage Category 2A
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3Labeling according GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements
IrritantSignal Word: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P362: Take off contaminated clothing and wash before reuse.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+ P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.3. Composition/Information on Ingredients
Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-24. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.5. Fire Fighting Measures
Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Fire: Slightly flammable on heating.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures or when moistened under fire conditions, it may produce toxic or irritating fumes. Containers may explode on heating.6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid touching the spilled material. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating as per law.7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Specified.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.9. Physical and Chemical Properties
Appearance: Colorless white powder or crystals.
Odor: Faint to None.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is soluble in water.
Viscosity: Not available.
Molecular Weight: 436.4
Chemical Formula: C12H10CaO10S2-H2O10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles and heat.11. Toxicological Information
Acute toxicity: Harmful if inhaled. Irritating to skin and eyes.
Toxicity data:
LD50: Oral: Rat: 7061 mg/Kg
LD50: Intravenous: Rat: 750 mg/Kg
LD50: Intraperitoneal: Mouse: 876 mg/Kg
Carcinogenic Effects: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Mutagenic Effects: NA
Teratogenic Effects: NA
Developmental Toxicity: NA.12. Ecological Information
Environmental Toxicity: Not available.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
USA DOT & ADR/RID Classification: Not regulated.
Canada TDG Classification: Not regulated.
IATA: Not regulated.15. Regulatory Information
USA:
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
SARA 311/312: Immediate health hazard. See section 2.Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Calcium Dobesilate Monohydrate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564e-mail: info@kingofchemicals.com
Copyright and Usual Disclaimer is Applicable --- October 23, 2024
If I give you “My Word” Nobody can undo it.
If I sign an “Agreement” my Lawyer will undo itOur products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard.Atorvastatin Calcium Calcium Dobesilate Monohydrate Calcium Folinate Hydrate Calcium Lactobionate