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Specifications, Properties, Uses, SDS of Magnesium Pidolate BP Ph Eur Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 62003-27-4.
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Magnesium Pidolate CAS Number 62003-27-4For Properties Specifications Uses of Magnesium Pidolate Click Properties, Specifications, Uses, Price, Process of Magnesium Pidolate Manufacturer.
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The Properties, Specifications, Monograph and Uses of Magnesium Pidolate:
CAS Number: 62003-27-4, EINECS EC Number: 263-365-7, Molecular Formula: C10H12N2O6Mg, Molecular Weight: 280.5 HS Code 29181620
Magnesium pidolate, the magnesium salt of pidolic acid (pyroglutamic acid), is a mineral supplement, which contains 8.664% magnesium. The Pharmaceutical industry uses Magnesium Pidolate to manufacture drugs for patients who suffer from Magnesium deficiencies. Magnesium Pidolate is also used as a supplement in the Nutraceutical and the Animal Nutrition industry.
Magnesium Pidolate BP Ph Eur Grade Specifications
C10H12N2O6Mg -- 280.5 -- CAS 62003-27-4DEFINITION
Magnesium bis[(2S)-5-oxopyrrolidine-2-carboxylate].
Content: 8.49 per cent to 8.84 per cent of Mg (Ar = 24.31) (anhydrous substance).CHARACTERS
Appearance: Amorphous, white or almost white powder, hygroscopic.
Solubility: Very soluble in water, soluble in methanol, practically insoluble in methylene chloride.IDENTIFICATION
A. Thin-layer chromatography. To pass the test.
B. To 0.15 ml of solution S (see Tests) add 1.8 ml of water. The solution gives the reaction of magnesium.TESTS
Solution S: Dissolve 5.00 g in carbon dioxide-free water prepared from distilled water& and dilute to 50.0 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
pH: 5.5 to 7.0 for solution S.
Specific optical rotation: - 23.3 to - 26.5 (anhydrous substance), determined on solution S.
Related substances: To pass the test by Liquid chromatography for impurity B and Thin-layer chromatography for impurity A
Chlorides: Maximum 500 ppm.
Nitrates: Examine the chromatogram obtained with the test solution in the test for related substances.
Limit: nitrates: not more than the area of the principal peak in the chromatogram obtained with reference solution (d) (200 ppm).
Sulphates: Maximum 0.1 per cent.
Arsenic: Maximum 2 ppm.
Iron: Maximum 200 ppm.
Heavy metals: Maximum 20 ppm.
Water: Maximum 8.0 per cent, determined on 0.200 g.ASSAY
Dissolve 0.300 g in 50 ml of water. Carry out the complexometric titration of magnesium.
1 ml of 0.1 M sodium edetate is equivalent to 2.431 mg of Mg.IMPURITIES
A. glutamic acid,
B. (2S)-2-[[[(2S)-5-oxopyrrolidin-2-yl]carbonyl]amino]pentanedioic acid.
The MSDS-SDS Hazard Statement of Magnesium Pidolate:
Magnesium Pidolate SDS GHS, Safety Data Sheet
MSDS, Material Safety Data Sheet 20-Jul-21Section 1: Chemical Product and Company Identification
Product Name & Other Names: Magnesium Pidolate or Magnesium salt of pidolic acid.
Synonym: Magnesium salt of pidolic acid, Pyroglutamic acid, Magnesium (S)-2-pyrrolidone-5-carboxylate, Magnesium 5-oxo-L-proline.
CAS Number: 62003-27-4
EINECS EC Code: 263-365-7
Molecular Formula: C10H12N2O6Mg
Molecular Weight: 280.5
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS
GHS Label Elements
NONESignal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.Section 3: Composition and Information on Ingredients
Product Name & Other Names: Magnesium Pidolate or Magnesium salt of pidolic acid.
Synonym: Magnesium salt of pidolic acid, Pyroglutamic acid, Magnesium (S)-2-pyrrolidone-5-carboxylate, Magnesium 5-oxo-L-proline.
CAS Number: 62003-27-4
EINECS EC Code: 263-365-7Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: Carbon oxides, nitrogen oxides (NOx), Magnesium oxide.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and acids. Hygroscopic.Section 8: Exposure Controls/Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. There is a blanket recommendation of 10 mg/m3 for inspirable dusts or mists when limits have not otherwise been established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants low.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice.Section 9: Physical and Chemical Properties
Physical state and appearance: Solid white crystals or powder.
Odor: Not available.
Odor threshold: Not available.
pH (10% soln/water): about 5.5 to 7.
Relative density: Not available.
Melting Point: Not available..
Boiling Point: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Formula: C10H12N2O6Mg
Molecular Weight: 280.5Section 10: Stability and Reactivity Data
Stability: It is stable in closed containers under recommended storage & handling.
Conditions of instability: Incompatible materials, Moisture
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.Section 11: Toxicological Information
Toxicological Data: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.Section 12: Ecological Information
Toxicity to Fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMDG/IMO: Not dangerous goods.
Air Transport IATA/ICAO: Not dangerous goods.Section 15: Other Regulatory Information
USA Regulations:
SARA 311/312 Hazards: No SARA Hazards. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.Section 16 - Additional Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Magnesium Pidolate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564e-mail: info@kingofchemicals.com
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We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard.