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Specifications, Properties, Uses, SDS of Choline Bitartrate Choline Bitartrate or Choline Acid Tartrate or Choline Hydrogen Tartrate USP Dietary Supplement & FCC Food Grade Manufacturer Supplier Exporter Wholesale & Small Packs, CAS Number 87-67-2. |
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Muby Chem Pvt. Ltd. is a several decades old group of companies, engaged in manufacturing, supplying, distributing, wholesale supplies of Choline Bitartrate or Choline Acid Tartrate or Choline Hydrogen Tartrate for actual users, including retail or small pack supplies for research and development work.
We supply fine and speciality chemicals, pharmaceutical excipients, mineral fortifiers in chemically pure, analytical reagent grade, IP BP USP Ph Eur EP JP and other pharmaceutical grade monograph including FCC Food grade chemicals and Nutraceuticals at best prices. We and/or our associated units have all the facilities to supply as per cGMP standard observing good manufacturing practice and good laboratory practice. We can assure low microbial count and also offer a test certificate for the same. We maintain warehouses across USA, India, and UAE. Our group exports to USA, Canada, Mexico, Argentina, Brazil, Chile, Korea, Malaysia, Thailand, Indonesia, Europe, and several other parts of the world. We supply in wholesale container loads to small pack of few grams. Solid products may be specified for it size and shape as desired by the buyer.
Choline Bitartrate or Choline Acid Tartrate or Choline Hydrogen Tartrate CAS Number 87-67-2
For Properties Specifications Uses of Choline Bitartrate Click Properties, Specifications, Uses, Price, Process of Micro-encapsulated Choline Bitartrate Manufacturer.
For For SDS MSDS Sheet of Choline Bitartrate Click SDS Safety Data Sheet MSDS Sheet of Micro-encapsulated Choline Bitartrate Manufacturer.
The Properties, Specifications, Monograph and Uses of Choline Bitartrate:
CAS Number: 87-67-2, EINECS EC Number: 201-763-4, Molecular Formula: C9H19NO7 or [HOCH2CH2N (CH3)3]C4H5O6, Molecular Weight: 253.25, HS Code 29231000 or 29420090
Choline Bitartrate is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. It is used in food and feed supplements.
Choline Bitartrate USP Dietary Supplement Grade:
C9H19NO7 --- 253.25
2-Hydroxyethanaminium, -N,N,N-trimethyl-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1);
(2-Hydroxyethyl)trimethylammonium-l-(+)-tartrate salt (1:1) CAS 87-67-2
DEFINITION
Choline Bitartrate contains NLT 99.0% and NMT 100.5% of choline bitartrate (C9H19NO7), calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption
B.
Sample: 1 g
Analysis: Dissolve the Sample in 20 mL of water and add 2 mL of potassium chloride solution (1 in 4).
Acceptance criteria: A white precipitate of potassium bitartrate is formed.
ASSAY
To pass the test.
Acceptance criteria: 99.0% to 100.5% on the anhydrous basis.
Residue on Ignition: NMT 0.1%
Arsenic: NMT 2 ppm
Lead: To pass the test. --- (NMT 0.3 ppm).
Limit of Total Amines: To pass the test.
Acceptance criteria: NMT 10 µg/g
Chromatographic Purity:
Acceptance criteria
Individual impurities: NMT 0.3%
Total impurity: NMT 2.0%
Optical Rotation, Specific Rotation:
Sample solution: 400 mg/mL in water
Acceptance criteria: +17.5° to +18.5°
pH: 3.0 to 4.0, in a solution (1 in 10)
Water Determination: NMT 0.5%
Packaging and Storage: Preserve in well-closed containers.
Choline Bitartrate FCC Food Grade Specifications:
(2-Hydroxyethyl)trimethylammonium-L-(+)-tartrate Salt
[HOCH2CH2N (CH3)3]C4H5O6
C9H19NO7 Formula weight 253.25
INS: 1001(v) CAS: 87-67-2
DESCRIPTION
Choline Bitartrate occurs as a white, hygroscopic, crystalline powder. It is freely soluble in water, slightly soluble in alcohol, and insoluble in ether and in chloroform.
Function: Nutrient.
REQUIREMENTS
Identification:
A. Dissolve 500 mg of sample in 2 mL of water, add 3 mL of 1 N sodium hydroxide, and heat to boiling. The odor of trimethylamine is detectable.
B. Dissolve 500 mg of sample in 2 mL of iodine. A red-brown precipitate forms immediately. Add 5 mL of 1 N sodium hydroxide. The precipitate dissolves, and the solution becomes clear yellow. Heat the solution. A pale yellow precipitate forms.
C. Add 1 mL of a 1:100 aqueous solution and 2 mL of a 1:50 solution of potassium ferrocyanide to 2 mL of cobaltous chloride. An emerald green color develops immediately.
Assay: Not less than 98.0% of C9H19NO7, calculated on the anhydrous basis.
1,4-Dioxane: Passes test.
Lead: Not more than 2 mg/kg.
Optical (Specific) Rotation: Between: 17.5° and 18.5°.
Residue on Ignition: Not more than 0.1%.
Water: Not more than 0.5%.
We also manufacture Micro-Encapsulated Choline Bitartrate, having core of Choline Bitartrate and coating of vegetable oil or mono and diglycerides or as desired by the buyer. Encapsulation will make it slow release or extended release.
Please visit Micro-encapsulated Choline Bitartrate.
The MSDS-SDS Hazard Statement of Choline Bitartrate:
Choline Bitartrate SDS, Safety Data Sheet
MSDS, Material Safety Data Sheet 24-Aug-21
1. Product Identification
Product Name & Other Names: Choline Bitartrate or Choline Acid Tartrate or Choline Hydrogen Tartrate or 2-(Hydroxyethyl)trimethylammonium bitartrate.
CAS No.: 87-67-2
EINECS EC Number: 201-763-4
Molecular Weight: 253.25
Chemical Formula: C9H19NO7 or [HOCH2CH2N (CH3)3]C4H5O6
Relevant uses and uses advised against (if any): Industrial Manufacturing
SUPPLIER: As per Letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Choline Bitartrate or Choline Acid Tartrate or Choline Hydrogen Tartrate or 2-(Hydroxyethyl)trimethylammonium bitartrate.
CAS No.: 87-67-2
EINECS EC Number: 201-763-4
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion: Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing.
Skin Contact: Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.
5. Fire Fighting Measures
Fire: Not considered to be a fire hazard. It can burn at high temperature.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Use means suitable for extinguishing surrounding fire.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law. Shut off all possible sources of ignition.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong bases, acid anhydrides, acid chlorides. Hygroscopic.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Colorless or white powder.
Odor: Odorless.
Odor threshold: Not available.
pH: 3.0 - 4.4 at 50 g/l 20C
Relative density: around 1.98
Melting point: 149C to 153C
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Freely sol in water; slightly sol in alcohol; insoluble in ether, chloroform and benzene.
Viscosity: Not available.
Molecular Weight: 253.25
Chemical Formula: C9H19NO7 or [HOCH2CH2N (CH3)3]C4H5O6
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: When heated to decomposition, substance may emit toxic fumes, oxides of carbon and nitrogen will evolve under fire condition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, Strong bases, Acid anhydrides, Acid chlorides.
Conditions to Avoid: Incompatible products. Excess heat. Avoid dust formation. Exposure to moist air or water.
Hazardous Polymerization: Hazardous polymerization does not occur.
11. Toxicological Information
No LD50/LC50 information found relating to normal routes of occupational exposure.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Germ cell mutagenicity: Not available.
Reproductive toxicity: Not available.
Teratogenicity: Not available.
12. Ecological Information
Toxicity: Not available.
Persistence and degradability: Not available.
Mobility in soil: Not available.
Bioaccumulative potential: Not available.
Results of PBT and vPvB assessment: Not available.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with federal, state, and local requirements.
14. Transport Information
Land Transport DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
Sea Transport IMO/IMDG: Not dangerous goods.
Air Transport ICAO/IATA: Not dangerous goods.
15. Regulatory Information
SARA 311/312: See section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.
16. Other Information
DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources, and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules, or insurance requirements applicable. This SDS MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a professionally trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. This shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship. In no case shall our company be liable to loss or damages by the product user.
Choline Bitartrate Manufacturers, Suppliers, Exporters, Wholesalers:
King of Chemicals manufacturers
Plot No. 2900/46&47 + 2900/163to167, GIDC, Ankleshwar, Dist. Bharuch, India
India, USA, UAE
TEL: (Office) 91-22-23774610, 91-22-23723564
e-mail: info@kingofchemicals.com
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Our products are for industrial and laboratory use only. The user must test the material before use. We are not dispensing chemists or druggist and do not offer over the counter type (OTC) products for medical use by individuals.
We and our associates manufacture pure chemicals surpassing Monograph Specifications of Analytical Reagent Standards, British & European Pharmacopoeia BP Ph Eur EP Standard, US Pharmacopoeia USP NF Standard, Indian Pharmacopoeia IP Standard, Japan Pharmacopoeia JP Standard, FCC Food Grade Standard. |
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